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PCSK6

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

PCSK6 is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0823 Anti-PCSK6 (2D6) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 2D6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0824 Anti-PCSK6 (CBYC-P227) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human CBYC-P227 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1723 Anti-PCSK6 (2D6) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 2D6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1724 Anti-PCSK6 (CBYC-P227) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human CBYC-P227 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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