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SEC31A

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ2113 Anti-SEC31A (CBXS-5744) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5744 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2114 Anti-SEC31A (CBXS-6010) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Monkey CBXS-6010 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5537 Anti-SEC31A (CBXS-5744) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-5744 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5538 Anti-SEC31A (CBXS-6010) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Monkey CBXS-6010 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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