SH3BP2

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The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ2328 Anti-SH3BP2 (CBXS-4087) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-4087 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2329 Anti-SH3BP2 (CBXS-0342) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0342 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5752 Anti-SH3BP2 (CBXS-4087) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-4087 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5753 Anti-SH3BP2 (CBXS-0342) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-0342 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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