SIM2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ2379 Anti-SIM2 (CBXS-4873) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-4873 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2380 Anti-SIM2 (CBXS-0376) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0376 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2381 Anti-SIM2 (CBXS-1584) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-1584 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2382 Anti-SIM2 (CBXS-3502) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3502 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5803 Anti-SIM2 (CBXS-4873) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-4873 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5804 Anti-SIM2 (CBXS-0376) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-0376 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5805 Anti-SIM2 (CBXS-1584) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-1584 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5806 Anti-SIM2 (CBXS-3502) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-3502 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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