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SMC1A

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Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ2622 Anti-SMC1A (CBXS-5678) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-5678 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2623 Anti-SMC1A (CBXS-5934) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5934 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2624 Anti-SMC1A (CBXS-3890) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3890 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2625 Anti-SMC1A (CBXS-5281) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Monkey CBXS-5281 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2626 Anti-SMC1A (5B6) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse 5B6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2627 Anti-SMC1A (C2M) h(41BB-CD3ζ) CAR, pCDCAR1 Human C2M Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2628 Anti-SMC1A (CBXS-0549) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0549 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2629 Anti-SMC1A (CBXS-0550) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0550 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2630 Anti-SMC1A (CBXS-0551) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0551 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2631 Anti-SMC1A (CBXS-0552) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0552 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2632 Anti-SMC1A (CBXS-0553) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0553 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2633 Anti-SMC1A (CBXS-1236) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-1236 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2634 Anti-SMC1A (CBXS-1768) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXS-1768 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2635 Anti-SMC1A (CBXS-2295) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-2295 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2636 Anti-SMC1A (CBXS-2452) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2452 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2637 Anti-SMC1A (CBXS-2512) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2512 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2638 Anti-SMC1A (CBXS-2513) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2513 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2639 Anti-SMC1A (CBXS-2599) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2599 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2640 Anti-SMC1A (CBXS-2600) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2600 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2641 Anti-SMC1A (CBXS-2657) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBXS-2657 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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