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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MOREWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MOREUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don’t find the answers you’re looking for, contact us for additional assistance.
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TOSO, also known as Fas-inhibitory molecule 3 (FAIM3) or Fc mu receptor (FCMR) in humans is encoded by the FCMR gene. FCMR
was defined as a 60-kD transmembrane sialoglycoprotein and FCMR (TOSO) expression was up-regulated on B cells, but was down-modulated on T cells, suggesting differential regulation of TOSO expression during B and T cell activation. Human FCMR mRNA was strongly
expressed in hematopoietic tissues such as the spleen, thymus and peripheral blood leukocytes. Intracellular upregulation of Fc mu receptor (FCMR, FAIM3/TOSO) gene in the leukemic lymphocytes of the patients with CLL may be an important parameter in predicting the progression of the disease.
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
| CAR-LC125 | Anti-TOSO (6B10) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 6B10 | Rat | scFv-CD28-CD3ζ | Retroviral | T cell |
Nanoparticle Tiny Tech for Programming T Cells: A novel technology to increase the efficiency and value of your CAR-T therapy project.
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Angiotensin-converting Enzyme 2 (ACE2)-CHO Cell Line Model for COVID-19: Helps researchers to further study the interaction between the receptor ACE2 and the COVID-19 virus.
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TRAC-CAR-T Cell Development with CRISPR/Cas9 Technology: A novel technology to build more powerful CAR-T cells.
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