WNT1

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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP1259 WNT1 (FZD3 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1260 WNT1 (FZD8 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1261 WNT1 (FZD9 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1262 WNT1 (RYK Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2659 WNT1 (FZD3 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2660 WNT1 (FZD8 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2661 WNT1 (FZD9 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2662 WNT1 (RYK Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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