WNT3

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP228 WNT3 (FZD7 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1264 WNT3 (FZD8 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1265 WNT3 (LRP6 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1266 WNT3 (RYK Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1628 WNT3 (FZD7 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2664 WNT3 (FZD8 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2665 WNT3 (LRP6 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2666 WNT3 (RYK Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT3-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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