WNT4

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP1267 WNT4 (FZD2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT4-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1268 WNT4 (FZD6 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT4-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2667 WNT4 (FZD2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT4-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2668 WNT4 (FZD6 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human WNT4-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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