All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Creative Biolabs, as a pioneering service provider in the domain of antibody discovery and immunotherapy, boasts extensive expertise garnered over the years. We are excited to introduce our cutting-edge platform tailored to offer a γδ T cell receptor (TCR) T cell discovery service with therapeutic applications. This technology empowers patients to harness their T-cells to combat and eliminate tumor cells and infected cells.
Gamma delta (γδ) T cells represent a unique subset of T lymphocytes that differ from the more common αβ T cells in terms of their T cell receptor (TCR) structure. This structural difference endows γδ T cells with distinctive properties and functions.
Within the spectrum of TCRs, there exist two main types: αβ TCR and γδ TCR. γδ TCR-T cells typically constitute a small proportion of peripheral blood lymphocytes, they play a crucial role in human immune defense. When the physiological state undergoes changes, γδ T cells can effectively migrate and eliminate tumor cells without relying on antigen-presenting cell activation or lymphoid system cloning and expansion. This, in turn, triggers normal antigen presentation in the lymphoid system and activates a systemic immune response. The crux of γδ TCR's cancer cell recognition lies in identifying unique signal molecules expressed on their surface.
Fig.1 Enhance γδ T Cell Anti-Tumor Activity.1
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