Fas Ligand

FASLG (Fas Ligand) is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE).

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1531Lsx Recombinant Fas Ligand Protein (Pro 134-Leu 281) [His] HEK293 Cells. Human Fas Ligand (TNFSF6), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH17502.1) Fas Ligand Tumor Antigens Datasheet 50 µg Inquiry

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