Anti-CDK5 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0412-CQ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CDK5 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CDK5

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
1020

UniProt ID
Q00535

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0412-CQ	CBXC-2427	Mouse		IgG1, κ
DMAb-0413-CQ	CBXC-0324	Mouse		IgG2a
DMAb-0414-CQ	CBXC-0325	Mouse		IgG1, κ
DMAb-0415-CQ	CBXC-0326	Mouse		IgG
DMAb-0416-CQ	CBXC-2142	Mouse		IgG1	Protein expressed in 293T cell transfected with human CDK5 expression vector
DMAb-0417-CQ	CBXC-2027	Mouse		IgG1	Purified rat Cdk5
DMAb-2826-FY	CBFYC-1603	Mouse	Human	IgM, k
DMAb-2827-FY	CBFYC-1604	Mouse	Human		Recombinant CDK5 (Asp92~Gln273) expressed in E. coli
DMAb-2828-FY	CBFYC-1605	Mouse	Human	IgG1	Purified recombinant human CDK5 (N-terminal) protein fragments expressed in E. coli
DMAb-2829-FY	CBFYC-1606	Mouse	Human	IgG	Purified Rat Cdk5
DMAb-2830-FY	CBFYC-1607	Mouse	Human	IgG1	Recombinant protein from human
DMAb-2831-FY	CBFYC-1608	Mouse	Human	IgG1, k	His-tagged, recombinant human CDK5 protein purified from E.coli
DMAb-2832-FY	CBFYC-1609	Mouse	Human	IgG2b, k	His-tagged, recombinant human CDK5 protein purified from Baculovirus expressed in insect cells
DMAb-2833-FY	CBFYC-1610	Mouse	Human	IgG1, k	This CDK5 antibody is generated from a mouse immunized with a recombinant protein of human CDK5
DMAb-2834-FY	CBFYC-1611	Mouse	Human	IgG1	Recombinant cdk5 protein
DMAb-0141-CN	EP715Y	Rabbit	Human	IgG	Synthetic peptide corresponding to residues in the C-terminus of human Cdk5

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CDK5 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0412-CQ)

Specifications

Target

Customer Reviews and Q&As

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