Anti-LCK DNA-encoded mAb (DMAb), pVAX1 (DMAb-0043-YJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-LCK DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

Add to Cart

Specifications

Target
LCK

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
3932

UniProt ID
P06239

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0043-YJ	1526CT823.75.16	Mouse	Human	IgG1, κ	This LCK antibody is generated from a mouse immunized with a recombinant protein.
DMAb-0044-YJ	33D196	Mouse		IgG1	This monoclonal antibody was raised against a synthetic peptide containing amino acid residues of human lck protein.
DMAb-0027-YJ	3A5	Mouse		IgG2b, κ	Recombinant protein corresponding to aa 1-225 of murine p56lck protein.
DMAb-0046-YJ	3E5-C8-B9	Mouse	Human	IgG1	Purified recombinant human LCK protein fragments expressed in E. coli.
DMAb-0047-YJ	845CT3-5-2	Mouse	Human	IgG1	Purified His-tagged LCK protein was used to produced this monoclonal antibody.
DMAb-0048-YJ	8E5F9	Mouse	Human	IgG2a
DMAb-0049-YJ	LCK-01	Mouse	Human	IgG1	Peptide corresponding to amino acids 22-36 in the sequence of human Lck.
DMAb-0050-YJ	7H125	Mouse	Human	IgG	E. coli-derived recombinant human Lck (aa 1-66) UniProt # P06239.

Customer Reviews and Q&As

There are currently no customer reviews or questions for Anti-LCK DNA-encoded mAb (DMAb), pVAX1 (DMAb-0043-YJ). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-LCK DNA-encoded mAb (DMAb), pVAX1 (DMAb-0043-YJ)

Specifications

Target

Customer Reviews and Q&As

Related Products

CAR Vector Products