Next-Generation Sequencing based Tumor Mutation Burden (TMB) Analysis Service

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Welcome to our Next-Generation Sequencing (NGS) based Tumor Mutation Burden (TMB) Analysis Service. At Creative Biolabs, we are committed to providing cutting-edge genomic analysis services that empower researchers and clinicians to delve deeper into the genetic landscape of tumors. Our NGS-based TMB analysis offers a crucial tool for understanding tumor genetics and enhancing personalized medicine, enabling better treatment decisions and improved outcomes.

Understanding TMB

The total amount of somatic mutations that a tumor has is known as the tumor mutation burden. In oncology, especially in the area of immunotherapy, it is becoming a prominent biomarker. Research has demonstrated that tumors with high mutation burdens are more likely to produce neoantigens-novel protein fragments that arise from mutated genes. This increases the likelihood that the immune system will identify and target these cancer cells. Conversely, low TMB may correlate with a lesser response to immune checkpoint inhibitors and other forms of immunotherapy.

By assessing the TMB of a tumor, clinicians gain valuable insights into the likelihood of a patient's response to treatment, making TMB a powerful tool for guiding personalized care strategies. With the rising importance of precision medicine, our NGS-based TMB analysis offers significant advantages in uncovering the genetic factors that influence treatment efficacy.

NGS-Based TMB Analysis Service at Creative Biolabs

Our NGS-Based TMB Analysis Service combines a detailed and systematic workflow with advanced technological features to offer reliable and insightful genomic analysis. By choosing our service, you gain access to high-quality data that can significantly enhance your understanding of tumor genetics and inform personalized treatment strategies.

Workflow

Our Next-Generation Sequencing (NGS) Based Tumor Mutation Burden (TMB) Analysis Service follows a systematic workflow designed to ensure accuracy, reliability, and efficiency.

Fig.1 Process. (Creative Biolabs Original)

Sample Types

Fresh tumor biopsies, formalin-fixed paraffin-embedded (FFPE) tissues, and blood samples are among the many sample types that we accept.

Technical Features

High Sensitivity and Specificity: Utilizing advanced NGS technology allows us to detect low-frequency mutations with high accuracy, ensuring that even subtle changes in the tumor genome are identified.

Broad Coverage: Our approach allows for comprehensive sequencing of both coding and non-coding regions of the genome, providing a holistic view of genetic changes that may influence tumor behavior and treatment responses.

Comprehensive Bioinformatics: We employ the latest bioinformatics tools and pipelines, which include alignment, variant calling, and annotation processes that are crucial for the accurate interpretation of TMB and mutation profiles.

Quality Assurance Protocols: Rigorous quality assurance protocols at every stage—from sample handling to data analysis—ensure the integrity and reliability of our results, allowing you to trust the data for clinical or research applications.

Real-Time Monitoring: Our system allows for real-time monitoring and quality control during the sequencing process, enabling rapid identification and correction of any issues that may arise.

Why Choose Creative Biolabs

Choosing our NGS-based TMB analysis service comes with numerous benefits:

Fig.2 Advantages. (Creative Biolabs Original)

Get Started Today

At Creative Biolabs, we are excited to support your research endeavors through our Next-Generation Sequencing-based Tumor Mutation Burden Analysis Service. Understanding the genetic makeup of tumors is pivotal in the fight against cancer, and our services are tailored to empower you with the essential insights needed to make informed decisions.

Please do not hesitate to contact us if you would like to discuss your specific needs or if you have any queries about our TMB analysis services. Our dedicated staff is on hand to answer your questions and provide the support you need. Together, let's unlock the potential of genomic insights to advance cancer treatment and research. Reach out today via email or phone, and take the next step in your journey toward personalized oncology.

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.