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HMW-MAA

Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that in humans is encoded by the CSPG4 gene. CSPG4 plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. It represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. Human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

Associated Disease
  • Metastatic melanoma
  • Melanoma
  • CAR Vector Products
  • CAR Viral Particles
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  • Receptor Construction:
CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M318-2 Anti-HMW-MAA scFv h(CD28) CART, pCDCAR1 Human 225.28S Mouse scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M318-G Anti-HMW-MAA scFv h(FcεRIγ) CART, pCDCAR1 Human 225.28S Mouse scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M318-Z Anti-HMW-MAA scFv h(CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M318-2G Anti-HMW-MAA scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M318-2Z Anti-HMW-MAA scFv h(CD28-CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M318-4G Anti-HMW-MAA scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M318-4Z Anti-HMW-MAA scFv h(CD4-CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M318-8Z Anti-HMW-MAA scFv h(CD8-CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M318-BZ Anti-HMW-MAA scFv h(41BB-CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M318-CZ Anti-HMW-MAA scFv h(b2c-CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M318-2BZ Anti-HMW-MAA scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M318-2XZ Anti-HMW-MAA scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human 225.28S Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet

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