HMW-MAA

Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that in humans is encoded by the CSPG4 gene. CSPG4 plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. It represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. Human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

Associated Disease
  • Metastatic melanoma
  • Melanoma

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-T-1-M318-2 T cell First 225.28S 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-M318-G T cell First 225.28S 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-M318-Z T cell First 225.28S 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-2-M318-2G T cell Second 225.28S 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-M318-2Z T cell Second 225.28S 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-M318-4G T cell Second 225.28S 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-M318-4Z T cell Second 225.28S 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-M318-8Z T cell Second 225.28S 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-M318-BZ T cell Second 225.28S 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-M318-CZ T cell Second 225.28S 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-3-M318-2BZ T cell Third 225.28S 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-M318-2XZ T cell Third 225.28S 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC169 225.28S Lentivirus First scFv (225.28S)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC170 225.28S Lentivirus First scFv (225.28S)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC171 225.28S Lentivirus First scFv (225.28S)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC172 225.28S Lentivirus Second scFv (225.28S)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC173 225.28S Lentivirus Second scFv (225.28S)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC174 225.28S Lentivirus Second scFv (225.28S)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC175 225.28S Lentivirus Second scFv (225.28S)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC176 225.28S Lentivirus Second scFv (225.28S)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC177 225.28S Lentivirus Second scFv (225.28S)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC178 225.28S Lentivirus Second scFv (225.28S)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC179 225.28S Lentivirus Third scFv (225.28S)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC180 225.28S Lentivirus Third scFv (225.28S)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
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USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-048-3343

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