IL6ST

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The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YY2665 Anti-IL6ST (10.51) h(41BB-CD3ζ) CAR, pCDCAR1 Human 10.51 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY2666 Anti-IL6ST (CBYY-C2576) h(41BB-CD3ζ) CAR, pCDCAR1 Rat CBYY-C2576 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY3032 Anti-IL6ST (10.51) h(CD28-CD3ζ) CAR, pCDCAR1 Human 10.51 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY3033 Anti-IL6ST (CBYY-C2576) h(CD28-CD3ζ) CAR, pCDCAR1 Rat CBYY-C2576 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-CQ7193 Anti-IL6ST (CBXC-1864) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-1864 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7194 Anti-IL6ST (CBXC-1856) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-1856 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7195 Anti-IL6ST (CBXC-1841) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-1841 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7196 Anti-IL6ST (CBXC-1844) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-1844 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7197 Anti-IL6ST (CBXC-1853) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-1853 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7673 Anti-IL6ST (CBXC-1864) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXC-1864 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7674 Anti-IL6ST (CBXC-1856) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXC-1856 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7675 Anti-IL6ST (CBXC-1841) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXC-1841 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7676 Anti-IL6ST (CBXC-1844) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXC-1844 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7677 Anti-IL6ST (CBXC-1853) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXC-1853 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6757 Anti-IL6ST (CBFYH-3280) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-3280 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6761 Anti-IL6ST (CBFYH-2592) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYH-2592 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6764 Anti-IL6ST (CBFYH-2594) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2594 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6772 Anti-IL6ST (CBFYH-2593) h(41BB-CD3ζ) CAR, pCDCAR1 Rat CBFYH-2593 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6884 Anti-IL6ST (CBFYH-2590) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYH-2590 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6885 Anti-IL6ST (CBFYH-2591) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2591 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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