MAGE-A4

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

Associated Disease
  • Esophageal cancer

TCR Vector Products Product list:

Catalog Target Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Vector
Type
Epitope Format HLA Data
sheet
Price
TCR-C131Z MAGE-A4 Human 2-28 Human ~8kb Lentiviral NYKRCFPVI Codon optimized HLA-A*2402 Inquiry
TCR-L062Z MAGE-A4 Human Human 8kb Lentiviral NYKRCFPVI Non-modified HLA-A2 Inquiry
TCR-L063 MAGE-A4 Human Human 6000bp retroviral vector NYKRCFPVI Non-modified TCR HLA-A2 Inquiry
TCR-L394 MAGE-A4 Human 2-28 Human ~8kb Lentiviral aa 143-151 Non-modified HLA-A24 Inquiry

TCR Viral Particles Product list:

Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Packaging
System
Epitope Format Titer Data
sheet
Price
VP-TCR-C256 Human 2-28 Human Lentivirus NYKRCFPVI Codon optimized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C257 Human 2-28 Human Lentivirus aa 143-151 Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C258 Human Human Lentivirus NYKRCFPVI Non-modified TCR > 10⁷ IFU/ml Inquiry
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