This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

Associated Disease
  • Esophageal cancer
  • TCR Vector Products
  • TCR Viral Particles
CAT Product Name Target Species Antibody Clone Antibody Host Epitope HLA Vector Type  
TCR-C131Z Human anti-MAGE-A4 T cell receptor (Codon optimized) (2-28), pCDTCR1 Human 2-28 Human NYKRCFPVI HLA-A*2402 Lentiviral   Inquiry
TCR-L062Z Human anti-MAGEA4 (aa143-151) T cell receptor, pCDTCR1 Human Human NYKRCFPVI HLA-A2 Lentiviral   Inquiry
TCR-L394 Human anti-MAGE-A4 T cell receptor (2-28), pCDTCR1 Human 2-28 Human aa 143-151 HLA-A24 Lentiviral   Inquiry
TCR-L063 Human anti-MAGEA4 (NYKRCFPVI) T Cell Receptor, pMX-IRES-GFP Human Human NYKRCFPVI HLA-A2 retroviral vector   Inquiry

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