Close
Close

Anti-RT T cell receptor (115 D7), pCDTCR1 (TCR-C233Z)

The vector of anti-RT T cell receptor (TCR) is constructed for the engineering of T cell to target HIV-1 RT. The T cells are genetically modified through transduction with a lentiviral vector expressing RT-specific T cell receptor. And the vector product was designed for the treatment of HIV-1 infection.

Datasheet   Add to Cart

Details

  • Target
  • RT
  • Target Species
  • HIV-1
  • Epitope
  • IYLALQDSGLEVNIVTDSQYALG
  • Format
  • Non-modified
  • HLA
  • HLA-B14
  • Targeting Diseases
  • HIV-1 infection
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • 115 D7
  • Antibody Host
  • Human

Target

  • Gene Name
  • Reverse transcriptase
  • Official Symbol
  • RT
  • Synonyms
  • HIV 1 Reverse transcriptase; HIV 1 RT; HIV RT; HIV1 RT; Human Immunodeficiency virus 1; Immuno Deficiency Virus Reverse Transcriptase
  • Introduction
  • Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. The four major routes of transmission are unsafe sex, contaminated needles, breast milk, and transmission from an infected mother to her baby at birth (perinatal transmission). Screening of blood products for HIV has largely eliminated transmission through blood transfusions or infected blood products in the developed world. HIV-1 reverse transcriptase from human immunodeficiency virus type 1 has two subunits, which have respective molecular weights of 66 and 51 kDa.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products

Online Inquiry
Products

CONTACT US

45-1 Ramsey Road, Shirley, NY 11967, USA
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:

Online Inquiry

For any technical issues or products/services related questions, please leave your contacts as below, and our team will contact you at earliest convenience to let you know how we can be involved in your projects.

  • Verification code

Key Updates

Receive the latest news and insights to your inbox.
Copyright © 2007 - 2019 Creative Biolabs. All Rights Reserved

Cart

    Go to checkout