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Lenti-RT TCR (HA1)-VP (VP-TCR-C472)

The ready-to-use lentiviral particles of Lenti-RT TCR (HA1)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of Human TCR will be driven by a CMV promotor. The target gene of TCR packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

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Specifications

  • Type of Therapeutics
  • T cell receptor
  • Target
  • RT
  • Clone
  • HA1
  • Promotor
  • CMV
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • HIV-1 infection

Target

  • Introduction
  • Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. The four major routes of transmission are unsafe sex, contaminated needles, breast milk, and transmission from an infected mother to her baby at birth (perinatal transmission). Screening of blood products for HIV has largely eliminated transmission through blood transfusions or infected blood products in the developed world. HIV-1 reverse transcriptase from human immunodeficiency virus type 1 has two subunits, which have respective molecular weights of 66 and 51 kDa.
  • Alternative Names
  • HIV 1 Reverse transcriptase; HIV 1 RT; HIV RT; HIV1 RT; Human Immunodeficiency virus 1; Immuno Deficiency Virus Reverse Transcriptase

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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