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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. The four major routes of transmission are unsafe sex, contaminated needles, breast milk, and transmission from an infected mother to her baby at birth (perinatal transmission). Screening of blood products for HIV has largely eliminated transmission through blood transfusions or infected blood products in the developed world. HIV-1 reverse transcriptase from human immunodeficiency virus type 1 has two subunits, which have respective molecular weights of 66 and 51 kDa.
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| CAT | Product Name | Target Species | TCR Clone | Host Species | Epitope | Allele | Vector Type | Inquiry & Datasheet |
| TCR-C226Z | Human anti-RT T cell receptor (3B), pCDTCR1 | HIV-1 | 3B | Human | TAFTIPSI | HLA-B51 | Lentiviral | |
| TCR-C227Z | Human anti-RT (IPLTEEAEL) T cell receptor, pCDTCR1 | HIV-1 | Human | IPLTEEAEL | HLA-B*3501 | Lentiviral | ||
| TCR-C228Z | Human anti-RT T cell receptor (2B5), pCDTCR1 | HIV-1 | 2B5 | Human | TAFTIPSI | HLA-B*51:01 | Lentiviral | |
| TCR-C229Z | Human anti-RT T cell receptor (HA1), pCDTCR1 | HIV-1 | HA1 | Human | aa 476-484 | HLA-A2 | Lentiviral | |
| TCR-C230Z | Human anti-RT T cell receptor (HA2), pCDTCR1 | HIV-1 | HA2 | Human | aa 476-484 | HLA-A2 | Lentiviral | |
| TCR-C231Z | Human anti-RT T cell receptor (HA3), pCDTCR1 | HIV-1 | HA3 | Human | aa 476-484 | HLA-A2 | Lentiviral | |
| TCR-C232Z | Human anti-RT T cell receptor (HA4), pCDTCR1 | HIV-1 | HA4 | Human | aa 476-484 | HLA-A2 | Lentiviral | |
| TCR-C233Z | Human anti-RT T cell receptor (115 D7), pCDTCR1 | HIV-1 | 115 D7 | Human | IYLALQDSGLEVNIVTDSQYALG | HLA-B14 | Lentiviral | |
| TCR-YC1051 | Mouse anti-RT T cell receptor (P14), pCDTCR1 | Mouse | P14 | Mouse | KAIYRFNAI | H2-Dᵇ | Lentiviral vector |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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