This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.

Associated Disease
  • Arthritis
  • TCR Vector Products
  • TCR Viral Particles
  • Vector Type:
CAT Product Name Target SpeciesAntibody CloneAntibody HostEpitopeHLAVector Type Inquiry & Datasheet
TCR-L007 Human anti-ACAN (ATEGRVRVNSAYQDK) T Cell Receptor, pMSGV1 Human Human ATEGRVRVNSAYQDK HLA–DR4+/DQ8 retroviral vector   Add to Cart   Datasheet
TCR-L007Z Human anti-ACAN (aa89-103) T cell receptor, pCDTCR1 Human Human ATEGRVRVNSAYQDK HLA–DR4+/DQ8 Lentiviral   Add to Cart   Datasheet

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