Close

anti-ACAN (aa89-103) TCR, pCDTCR1 (TCR-L007Z)

The vector of anti-ACAN T cell receptor (TCR) is constructed for the engineering of T cell to target Human ACAN. The T cells are genetically modified through transduction with a retroviral vector expressing ACAN-specific T cell receptor. And the vector product was designed for the treatment of arthritis.

Datasheet   Add to Cart

Details

  • Target
  • ACAN
  • Target Species
  • Human
  • Epitope
  • ATEGRVRVNSAYQDK
  • Format
  • Non-modified
  • HLA
  • HLA–DR4+/DQ8
  • Targeting Diseases
  • Arthritis
  • Vector Name
  • pCDTCR1
  • Vector Length
  • 8kb
  • Vector Type
  • Lentiviral
  • Antibody Host
  • Human

Target

  • Gene Name
  • aggrecan
  • Official Symbol
  • ACAN
  • Synonyms
  • AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Arthritis
  • Introduction
  • This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products

Online Inquiry
Products

CONTACT US

45-1 Ramsey Road, Shirley, NY 11967, USA
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:

Online Inquiry

For any technical issues or products/services related questions, please leave your contacts as below, and our team will contact you at earliest convenience to let you know how we can be involved in your projects.

  • Verification code

Key Updates

Receive the latest news and insights to your inbox.