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EXPLORE MOREThe protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
CAR-M0217-YC | Anti-MBP (2H9) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 | Human | 2H9 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-M0218-YC | Anti-MBP (Clone 2) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 | Cattle | Clone 2 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-M0628-YC | Anti-MBP (2H9) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 | Human | 2H9 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-M0629-YC | Anti-MBP (Clone 2) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 | Cattle | Clone 2 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ6919 | Anti-MBP (CBX-001) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | CBX-001 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ6920 | Anti-MBP (CBX-051) h(CD28-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Sheep, Rabbit, Goat, Human | CBX-051 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ6921 | Anti-MBP (BA0318) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | BA0318 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ6922 | Anti-MBP (BA0080) h(CD28-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | BA0080 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ6923 | Anti-MBP (CBX-047) h(CD28-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | CBX-047 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ7399 | Anti-MBP (CBX-001) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | CBX-001 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ7400 | Anti-MBP (CBX-051) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Sheep, Rabbit, Goat, Human | CBX-051 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ7401 | Anti-MBP (BA0318) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | BA0318 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ7402 | Anti-MBP (BA0080) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | BA0080 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-CQ7403 | Anti-MBP (CBX-047) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | CBX-047 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-WFY7040 | Anti-MBP (CBFYM-1840) h(41BB-CD3ζ) CAR, pCDCAR1 | Rat | CBFYM-1840 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAR-WFY7838 | Anti-MBP (CBFYM-1840) h(CD28-CD3ζ) CAR, pCDCAR1 | Rat | CBFYM-1840 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | Add to Cart Datasheet |
CAT | Product Name | Target Species | TCR Clone | Host Species | Epitope | Allele | Vector Type | Inquiry & Datasheet |
TCR-L070 | Human anti-MBP [89-101] T Cell Receptor, pLXSN | Human | Human | MBP[89-101] | HLA-A2 | retroviral vector | Add to Cart Datasheet | |
TCR-L069Z | Human anti-MBP (aa89-101) T cell receptor, pCDTCR1 | Human | Human | MBP[89-101] | HLA-A2 | Lentiviral | Add to Cart Datasheet | |
TCR-C146Z | Murinized anti-MBP T cell receptor (Hy.2E11), pCDTCR1 | Human | Hy.2E11 | Murinized | ENPVVHFFKNIVTPR | HLA-DRB1*1501 | Lentiviral | Add to Cart Datasheet |
TCR-C147Z | Mouse anti-MBP T cell receptor (172.10), pCDTCR1 | Human | 172.10 | Mouse | SRGGASQYRPSQ | I-Au | Lentiviral | Add to Cart Datasheet |
TCR-C148Z | Human anti-MBP T cell receptor (Ob.1A12), pCDTCR1 | Human | Ob.1A12 | Human | ENPVVHFFKNIVTPR | HLA-DR2 | Lentiviral | Add to Cart Datasheet |
TCR-C149Z | Human anti-MBP T cell receptor (3A6), pCDTCR1 | Human | 3A6 | Human | VHFFKNIVTPRTP | HLA-DR2a | Lentiviral | Add to Cart Datasheet |
TCR-C150Z | Mouse anti-MBP (GGRASDYKSAH) T cell receptor (1.D9.B2), pCDTCR1 | Human | 1.D9.B2 | Mouse | GGRASDYKSAH | I-Au | Lentiviral | Add to Cart Datasheet |
TCR-C151Z | Mouse anti-MBP (KGFKGAYDAQG) T cell receptor (1.D9.B2), pCDTCR1 | Human | 1.D9.B2 | Mouse | KGFKGAYDAQG | I-Au | Lentiviral | Add to Cart Datasheet |
TCR-C152Z | Human anti-MBP T cell receptor (OB), pCDTCR1 | Human | OB | Human | aa 84-102 | HLA-DR2b | Lentiviral | Add to Cart Datasheet |
TCR-C153Z | Human anti-MBP T cell receptor (MS2-3C8), pCDTCR1 | Human | MS2-3C8 | Human | aa 111-129 | HLA-DR4 | Lentiviral | Add to Cart Datasheet |
TCR-C154Z | Human anti-MBP T cell receptor (Hy.1B11), pCDTCR1 | Human | Hy.1B11 | Human | ENPVVHFFKNIVTPR | HLA-DQ1 | Lentiviral | Add to Cart Datasheet |
TCR-C155Z | Human anti-MBP T cell receptor (Hy.1F9), pCDTCR1 | Human | Hy.1F9 | Human | aa 84-102 | HLA-DR2 | Lentiviral | Add to Cart Datasheet |
TCR-C156Z | Murinized anti-MBP T cell receptor, pCDTCR1 | Human | Murinized | KIFKLGGRDSRSGSPMARR | HLA-DR13 | Lentiviral | Add to Cart Datasheet | |
TCR-L269 | Human anti-MBP T cell receptor (Hy.2H9), pCDTCR1 | Human | Hy.2H9 | Human | aa 85-99 | HLA-DR2 | Lentiviral | Add to Cart Datasheet |
TCR-YC0656 | Mouse anti-MBP T cell receptor (172.1), pCDTCR1 | 172.1 | Mouse | RGGASQYRPSQ | H2-IAᵘ | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0657 | Mouse anti-Mbp T cell receptor (1934.4), pCDTCR1 | Mouse | 1934.4 | Mouse | RGGASQYRPSQ | H2-IAᵘ | Lentiviral vector | Add to Cart Datasheet |
TCR-YC0658 | Mouse anti-Mbp T cell receptor (1.B2.D9), pCDTCR1 | Mouse | 1.B2.D9 | Mouse | GGRASDYKSAH | H2-IAᵘ | Lentiviral vector | Add to Cart Datasheet |
TCR-YC0659 | Human anti-MBP T cell receptor (1F1E8hu), pCDTCR1 | 1F1E8hu | Human | ENPVVHFFKNIVTPR | HLA-DR2b | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0660 | Mouse anti-MBP T cell receptor (cl19), pCDTCR1 | cl19 | Mouse | RGGASQYRPSQ | H2-IAᵘ | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0661 | Human anti-MBP T cell receptor ((Hy.1B11)-1), pCDTCR1 | Hy.1B11 | Human | ANPVVHFFKNIVTPR | HLA-DRB1*15:01 | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0662 | Human anti-MBP T cell receptor ((Hy.1B11)-2), pCDTCR1 | Hy.1B11 | Human | EAPVVHFFKNIVTPR | HLA-DRB1*15:01 | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0663 | Human anti-MBP T cell receptor ((Hy.1B11)-3), pCDTCR1 | Hy.1B11 | Human | ENAVVHFFKNIVTPR | HLA-DRB5*01:01 | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0664 | Human anti-MBP T cell receptor ((Hy.1B11)-4), pCDTCR1 | Hy.1B11 | Human | ENPAVHFFKNIVTPR | HLA-DRB1*15:01 | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0665 | Human anti-MBP T cell receptor ((Hy.1B11)-5), pCDTCR1 | Hy.1B11 | Human | ENPVAHFFKNIVTPR | HLA-DRB1*15:01 | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0666 | Human anti-MBP T cell receptor ((Hy.1B11)-6), pCDTCR1 | Hy.1B11 | Human | ENPVVDFFKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0667 | Human anti-MBP T cell receptor ((Hy.1B11)-7), pCDTCR1 | Hy.1B11 | Human | ENPVVHFFKAIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0668 | Human anti-MBP T cell receptor ((Hy.1B11)-8), pCDTCR1 | Hy.1B11 | Human | ENPVVHFFKDIVTPR | HLA-DQA1*01:02/DQB1*05:02 | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0669 | Human anti-MBP T cell receptor ((Hy.1B11)-9), pCDTCR1 | Hy.1B11 | Human | ENPVVHFFKNAVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0670 | Human anti-MBP T cell receptor ((Hy.1B11)-10), pCDTCR1 | Hy.1B11 | Human | ENPVVHFFKNIVAPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0671 | Human anti-MBP T cell receptor ((Hy.1B11)-11), pCDTCR1 | Hy.1B11 | Human | ENPVVHFFKNIVTAR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0672 | Human anti-MBP T cell receptor ((Hy.1B11)-12), pCDTCR1 | Hy.1B11 | Human | ENPVVHFFKNIVTPA | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0673 | Human anti-MBP T cell receptor ((Hy.1B11)-13), pCDTCR1 | Hy.1B11 | Human | ENPVVHFFRNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0674 | Human anti-MBP T cell receptor ((Hy.1B11)-14), pCDTCR1 | Hy.1B11 | Human | ENPVVHFHKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0675 | Human anti-MBP T cell receptor ((Hy.1B11)-15), pCDTCR1 | Hy.1B11 | Human | ENPVVHFIKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0676 | Human anti-MBP T cell receptor ((Hy.1B11)-16), pCDTCR1 | Hy.1B11 | Human | ENPVVHFMKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0677 | Human anti-MBP T cell receptor ((Hy.1B11)-17), pCDTCR1 | Hy.1B11 | Human | ENPVVHFVKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0678 | Human anti-MBP T cell receptor ((Hy.1B11)-18), pCDTCR1 | Hy.1B11 | Human | ENPVVHFWKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0679 | Human anti-MBP T cell receptor ((Hy.1B11)-19), pCDTCR1 | Hy.1B11 | Human | ENPVVHFYKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0680 | Human anti-MBP T cell receptor ((Hy.1B11)-20), pCDTCR1 | Hy.1B11 | Human | ENPVVHGFKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TCR-YC0681 | Human anti-MBP T cell receptor ((Hy.1B11)-21), pCDTCR1 | Hy.1B11 | Human | ENPVVHMFKNIVTPR | HLA class II | Lentiviral vector | Add to Cart Datasheet | |
TLA-CA-353PZ | Anti-MBP (VHFFKNIVTPRTP) TCR-Like CAR [scFv (B-7-1)-BBζ], I-As-Restricted | Human | Autoimmunity | Mouse | VHFFKNIVTPRTP | I-As | Lentiviral vector | Add to Cart Datasheet |
TLA-CA-354PZ | Anti-MBP (VHFFKNIVTPRTP) TCR-Like CAR [scFv (B-18-7)-BBζ], I-As-Restricted | Human | Autoimmunity | Mouse | VHFFKNIVTPRTP | I-As | Lentiviral vector | Add to Cart Datasheet |
TLA-CA-355PZ | Anti-MBP (VHFFKNIVTPRTP) TCR-Like CAR [scFv (C34-72)-BBζ], I-As-Restricted | Human | Autoimmunity | Mouse | VHFFKNIVTPRTP | I-As | Lentiviral vector | Add to Cart Datasheet |
TLA-CA-360PZ | Anti-MBP (ENPVVHFFKNIVTPR) TCR-Like CAR [scFv (MK16)-BBζ], HLA-DR2b-Restricted | Human | Autoimmunity | ENPVVHFFKNIVTPR | HLA-DR2b | Lentiviral vector | Add to Cart Datasheet | |
TCR-LA-ZP168 | Anti-MBP (VHFFKNIVTPRTP) TCR-Like Antibody (B-7-1), I-As-Restricted | Human | B-7-1 | VHFFKNIVTPRTP | I-As | Add to Cart Datasheet | ||
TCR-LA-ZP169 | Anti-MBP (VHFFKNIVTPRTP) TCR-Like Antibody (B-18-7), I-As-Restricted | Human | B-18-7 | VHFFKNIVTPRTP | I-As | Add to Cart Datasheet | ||
TCR-LA-ZP170 | Anti-MBP (VHFFKNIVTPRTP) TCR-Like Antibody (C34-72), I-As-Restricted | Human | C34-72 | VHFFKNIVTPRTP | I-As | Add to Cart Datasheet | ||
TCR-LA-ZP175 | Anti-MBP (ENPVVHFFKNIVTPR) TCR-Like Antibody (MK16), HLA-DR2b-Restricted | Human | MK16 | ENPVVHFFKNIVTPR | HLA-DR2b | Add to Cart Datasheet |
CAT | Product Name | Target Species | DMAb Clone | DMAb Host | DMAb Isotype | DMAb Cross Reactivity | Vector Name | Inquiry & Datasheet |
DMAb-M217-YC | Mouse Anti-MBP DNA-encoded mAb (Clone 2H9), pVAX1 | Human | 2H9 | Mouse | IgG1 | Human | pVAX1 | Add to Cart Datasheet |
DMAb-M218-YC | Mouse Anti-MBP DNA-encoded mAb (Clone Clone 2), pVAX1 | Cattle | Clone 2 | Mouse | IgG1 | Cattle, Guinea pig, Human, Sheep, Rabbit, Rat | pVAX1 | Add to Cart Datasheet |
DMAb-3787-FY | Mouse Anti-MBP DNA-encoded mAb (CBFYM-1840), pVAX1 | Rat | CBFYM-1840 | Mouse | 0 | Rat | pVAX1 | Add to Cart Datasheet |
DMAb-3495CQ | Mouse Anti-MBP DNA-encoded mAb (Clone CBX-001), pVAX1 | Human | CBX-001 | Mouse | IgG2b | Human | pVAX1 | Add to Cart Datasheet |
DMAb-3496CQ | Mouse Anti-MBP DNA-encoded mAb (Clone CBX-051), pVAX1 | Human | CBX-051 | Mouse | IgG2b | Mouse, Rat, Sheep, Rabbit, Goat, Human | pVAX1 | Add to Cart Datasheet |
DMAb-3497CQ | Rabbit Anti-MBP DNA-encoded mAb (Clone BA0318), pVAX1 | Human | BA0318 | Rabbit | IgG | Human | pVAX1 | Add to Cart Datasheet |
DMAb-3498CQ | Rabbit Anti-MBP DNA-encoded mAb (Clone BA0080), pVAX1 | Human | BA0080 | Rabbit | IgG | Mouse, Rat, Human | pVAX1 | Add to Cart Datasheet |
DMAb-3499CQ | Rabbit Anti-MBP DNA-encoded mAb (Clone CBX-047), pVAX1 | Human | CBX-047 | Rabbit | IgG1 | Mouse, Rat, Human | pVAX1 | Add to Cart Datasheet |
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