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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MOREWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
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EXPLORE MOREUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don’t find the answers you’re looking for, contact us for additional assistance.
EXPLORE MOREThe protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
| CAR-M0217-YC | Anti-MBP (2H9) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 | Human | 2H9 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-M0218-YC | Anti-MBP (Clone 2) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 | Cattle | Clone 2 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-M0628-YC | Anti-MBP (2H9) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 | Human | 2H9 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-M0629-YC | Anti-MBP (Clone 2) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 | Cattle | Clone 2 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ6919 | Anti-MBP (CBX-001) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | CBX-001 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ6920 | Anti-MBP (CBX-051) h(CD28-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Sheep, Rabbit, Goat, Human | CBX-051 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ6921 | Anti-MBP (BA0318) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | BA0318 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ6922 | Anti-MBP (BA0080) h(CD28-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | BA0080 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ6923 | Anti-MBP (CBX-047) h(CD28-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | CBX-047 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ7399 | Anti-MBP (CBX-001) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | CBX-001 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ7400 | Anti-MBP (CBX-051) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Sheep, Rabbit, Goat, Human | CBX-051 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ7401 | Anti-MBP (BA0318) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | BA0318 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ7402 | Anti-MBP (BA0080) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | BA0080 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ7403 | Anti-MBP (CBX-047) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Mouse, Rat, Human | CBX-047 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-WFY7040 | Anti-MBP (CBFYM-1840) h(41BB-CD3ζ) CAR, pCDCAR1 | Rat | CBFYM-1840 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-WFY7838 | Anti-MBP (CBFYM-1840) h(CD28-CD3ζ) CAR, pCDCAR1 | Rat | CBFYM-1840 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell |
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