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The genetically modified anti-MBP TCR-NK cell is designed to target to the specific epitope-HLA complex. The TCR-NK is expected to show antigen-specific cytotoxicity against MBP antigen via the introduced TCR were successfully produced.
| Sub CAT. | HLA | TCR Clone | Epitope | |
| XS-0623-ZP63-SUB1 | HLA-DRB1*1501 | Hy.2E11 | ENPVVHFFKNIVTPR | |
| XS-0623-ZP63-SUB2 | I-Au | 172.10 | SRGGASQYRPSQ | |
| XS-0623-ZP63-SUB3 | HLA-DR2 | Ob.1A12 | ENPVVHFFKNIVTPR | |
| XS-0623-ZP63-SUB4 | HLA-DR2a | 3A6 | VHFFKNIVTPRTP | |
| XS-0623-ZP63-SUB5 | I-Au | 1.D9.B2 | GGRASDYKSAH | |
| XS-0623-ZP63-SUB6 | I-Au | 1.D9.B2 | KGFKGAYDAQG | |
| XS-0623-ZP63-SUB7 | HLA-DR2b | OB | aa 84-102 | |
| XS-0623-ZP63-SUB8 | HLA-DR4 | MS2-3C8 | aa 111-129 | |
| XS-0623-ZP63-SUB9 | HLA-DQ1 | Hy.1B11 | ENPVVHFFKNIVTPR | |
| XS-0623-ZP63-SUB10 | HLA-DR2 | Hy.1F9 | aa 84-102 | |
| XS-0623-ZP63-SUB11 | HLA-DR13 | KIFKLGGRDSRSGSPMARR | ||
| XS-0623-ZP63-SUB12 | HLA-DR2 | Hy.2H9 | aa 85-99 | |
| XS-0623-ZP63-SUB13 | HLA-DR13 | CB2A11 | KIFKLGGRDSRSGSPMARR |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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