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MDM2

This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Associated Disease
  • Cancer
  • CAR Vector Products
  • TCR Vector Products
  • TCR Viral Particles
  • DMAb
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  • Target Species:
  • Antibody Clone:
  • Antibody Host:
  • Receptor Construction:
CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-WFY2119 Anti-MDM2 (CBFYM-1959) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1959 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2120 Anti-MDM2 (CBFYM-1960) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1960 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2121 Anti-MDM2 (CBFYM-1961) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1961 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2122 Anti-MDM2 (CBFYM-1962) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYM-1962 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2123 Anti-MDM2 (CBFYM-1963) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYM-1963 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2124 Anti-MDM2 (CBFYM-1964) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBFYM-1964 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2125 Anti-MDM2 (CBFYM-1965) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYM-1965 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2112 Anti-MDM2 (CBFYM-0323) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYM-0323 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2113 Anti-MDM2 (CBFYM-0419) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBFYM-0419 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2114 Anti-MDM2 (CBFYM-0613) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-0613 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2115 Anti-MDM2 (CBFYM-1955) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1955 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2116 Anti-MDM2 (CBFYM-1956) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1956 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2117 Anti-MDM2 (CBFYM-1957) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1957 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2118 Anti-MDM2 (CBFYM-1958) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1958 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5371 Anti-MDM2 (CBFYM-1958) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1958 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5372 Anti-MDM2 (CBFYM-1959) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1959 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5373 Anti-MDM2 (CBFYM-1960) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1960 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5374 Anti-MDM2 (CBFYM-1961) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1961 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5375 Anti-MDM2 (CBFYM-1962) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYM-1962 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5376 Anti-MDM2 (CBFYM-1963) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYM-1963 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5377 Anti-MDM2 (CBFYM-1964) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBFYM-1964 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5378 Anti-MDM2 (CBFYM-1965) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBFYM-1965 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5365 Anti-MDM2 (CBFYM-0323) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYM-0323 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5366 Anti-MDM2 (CBFYM-0419) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBFYM-0419 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5367 Anti-MDM2 (CBFYM-0613) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-0613 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5368 Anti-MDM2 (CBFYM-1955) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1955 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5369 Anti-MDM2 (CBFYM-1956) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1956 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5370 Anti-MDM2 (CBFYM-1957) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1957 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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