Anti-MDM2 T cell receptor (MDM2), pCDTCR1 (TCR-L346)

The vector of anti-MDM2 T cell receptor (TCR) is constructed for the engineering of T cell to target Human MDM2. The T cells are genetically modified through transduction with a lentiviral vector expressing MDM2-specific T cell receptor.

Datasheet   Add to Cart


  • Target
  • MDM2
  • Target Species
  • Human
  • Epitope
  • aa 81-88
  • Format
  • Non-modified
  • Allele
  • H-2Kb
  • Targeting Diseases
  • Cancer
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • TCR Clone
  • MDM2
  • Host Species
  • Mouse


  • Official Symbol
  • MDM2
  • Introduction
  • This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products

Online Inquiry


USA: 45-1 Ramsey Road, Shirley, NY 11967, USA
Europe: Heidenkampsweg 58, 20097 Hamburg, Germany
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356

Online Inquiry

For any technical issues or products/services related questions, please leave your information below. Our team will contact you soon.

  • Verification code
    Click image to refresh the verification code.

Key Updates

Receive our latest news and insights.