Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsThe advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
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Cytomegalovirus (CMV) is a member of the herpes virus group which includes herpes simplex virus types 1 and 2; Varicella Zoster Virus, which causes chicken pox; and Epstein Barr virus, which causes infectious mononucleosis. These viruses remain dormant within the body over a long period. In humans, CMV is known as HCMV or human herpesvirus 5 (HHV-5). HHV-5 causes only a brief mononeucleosis-like malaise in immunocompetent adults, but may cause severe illness or death in immunosuppressed individuals. CMV pp65 is the early-late lower matrix phosphoprotein of CMV that may be relevant to the etiopathogenesis of scleroderma. CMV pp65 is a major constituent of the CMV virion bodies and is abundantly synthesized during lytic infection. In addition, the CMV pp65 protein is a frequent target for the exceptionally strong CMV-specific CD8(+) T cell response.
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| CAT | Product Name | Target Species | TCR Clone | Host Species | Epitope | Allele | Vector Type | Inquiry & Datasheet |
| TCR-L094 | Human anti-pp65 (NLVPMVATV) T Cell Receptor, pMP71 | Cytomegalovirus (CMV) | Human | NLVPMVATV | retroviral vector | |||
| TCR-L097 | Human anti-pp65 (NLVPMVATV) T Cell Receptor, pLXSN | CMV | Human | NLVPMVATV | HLA-A*0201 | retroviral vector | ||
| TCR-L098 | Human anti-pp65 (KYQEFFWDANDIYRI) T Cell Receptor, pLZRS | CMV | Human | KYQEFFWDANDIYRI | HLA-DRB1*0101 | retroviral vector | ||
| TCR-L099 | Human anti-pp65 (QYDPVAALF) T Cell Receptor, CSII-EF-MCS-IRES-hrGFP | CMV | Human | QYDPVAALF | lentiviral vector | |||
| TCR-L100 | Human anti-pp65 (TPRVTGGAM) T Cell Receptor, pMP71 | CMV | Human | TPRVTGGAM | HLA-B7 | retroviral vector | ||
| TCR-L101 | Human anti-pp65 (RPHERNGFTVL) T Cell Receptor, pMP71 | CMV | Human | RPHERNGFTVL | HLA-B7 | retroviral vector | ||
| TCR-L093Z | Human anti-pp65 (aa495-453) T cell receptor, pCDTCR1 | Cytomegalovirus (CMV) | Human | NLVPMVATV | Lentiviral | |||
| TCR-L096Z | Human anti-pp65 (aa495-503) T cell receptor, pCDTCR1 | CMV | Human | NLVPMVATV | HLA-A*0201 | Lentiviral | ||
| TCR-L097Z | Human anti-pp65 (aa509-523) T cell receptor (Codon optimized), pCDTCR1 | CMV | Human | KYQEFFWDANDIYRI | HLA-DRB1*0101 | Lentiviral | ||
| TCR-L098Z | Human anti-pp65 (aa341-349) T cell receptor, pCDTCR1 | CMV | Human | QYDPVAALF | Lentiviral | |||
| TCR-L099Z | Human anti-pp65 (aa417-426) T cell receptor (Codon optimized and cysteine modified), pCDTCR1 | CMV | Human | TPRVTGGAM | HLA-B7 | Lentiviral | ||
| TCR-L100Z | Human anti-pp65 (aa265-275) T cell receptor (Codon optimized and cysteine modified), pCDTCR1 | CMV | Human | RPHERNGFTVL | HLA-B7 | Lentiviral | ||
| TCR-C212Z | Human anti-pp65 T cell receptor (RA14), pCDTCR1 | CMV | RA14 | Human | NLVPMVATV | HLA-A2 | Lentiviral | |
| TCR-C213Z | Human anti-pp65 T cell receptor (12), pCDTCR1 | CMV | 12 | Human | IPSINVHHY | HLA-B35 | Lentiviral | |
| TCR-C214Z | Human anti-pp65 T cell receptor (JG-9), pCDTCR1 | CMV | JG-9 | Human | NLVPMVATV | HLA-A*0201 | Lentiviral | |
| TCR-C215Z | Human anti-pp65 T cell receptor (JG-33), pCDTCR1 | CMV | JG-33 | Human | NLVPMVATV | HLA-A*0201 | Lentiviral | |
| TCR-C216Z | Human anti-pp65 T cell receptor (MD-19), pCDTCR1 | CMV | MD-19 | Human | YSEHPTFTSQY | HLA-A*0101 | Lentiviral | |
| TCR-C217Z | Human anti-pp65 T cell receptor (BF-33/BF-38), pCDTCR1 | CMV | BF-33/BF-38 | Human | IPSINVHHY | HLA-B*3501 | Lentiviral | |
| TCR-C218Z | Human anti-pp65 T cell receptor (Codon optimized), pCDTCR1 | CMV | Human | NLVPMVATV | HLA-A2.1 | Lentiviral | ||
| TCR-C219Z | Human anti-pp65 T cell receptor (C7), pCDTCR1 | CMV | C7 | Human | NLVPMVATV | HLA-A2 | Lentiviral |
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The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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