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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
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EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Cytomegalovirus (CMV) is a member of the herpes virus group which includes herpes simplex virus types 1 and 2; Varicella Zoster Virus, which causes chicken pox; and Epstein Barr virus, which causes infectious mononucleosis. These viruses remain dormant within the body over a long period. In humans, CMV is known as HCMV or human herpesvirus 5 (HHV-5). HHV-5 causes only a brief mononeucleosis-like malaise in immunocompetent adults, but may cause severe illness or death in immunosuppressed individuals. CMV pp65 is the early-late lower matrix phosphoprotein of CMV that may be relevant to the etiopathogenesis of scleroderma. CMV pp65 is a major constituent of the CMV virion bodies and is abundantly synthesized during lytic infection. In addition, the CMV pp65 protein is a frequent target for the exceptionally strong CMV-specific CD8(+) T cell response.
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| CAT | Product Name | Target Species | TCR Clone | Host Species | Epitope | Allele | Vector Type | Inquiry & Datasheet |
| TCR-L094 | Human anti-pp65 (NLVPMVATV) T Cell Receptor, pMP71 | Cytomegalovirus (CMV) | Human | NLVPMVATV | retroviral vector | |||
| TCR-L097 | Human anti-pp65 (NLVPMVATV) T Cell Receptor, pLXSN | CMV | Human | NLVPMVATV | HLA-A*0201 | retroviral vector | ||
| TCR-L098 | Human anti-pp65 (KYQEFFWDANDIYRI) T Cell Receptor, pLZRS | CMV | Human | KYQEFFWDANDIYRI | HLA-DRB1*0101 | retroviral vector | ||
| TCR-L099 | Human anti-pp65 (QYDPVAALF) T Cell Receptor, CSII-EF-MCS-IRES-hrGFP | CMV | Human | QYDPVAALF | lentiviral vector | |||
| TCR-L100 | Human anti-pp65 (TPRVTGGAM) T Cell Receptor, pMP71 | CMV | Human | TPRVTGGAM | HLA-B7 | retroviral vector | ||
| TCR-L101 | Human anti-pp65 (RPHERNGFTVL) T Cell Receptor, pMP71 | CMV | Human | RPHERNGFTVL | HLA-B7 | retroviral vector | ||
| TCR-L093Z | Human anti-pp65 (aa495-453) T cell receptor, pCDTCR1 | Cytomegalovirus (CMV) | Human | NLVPMVATV | Lentiviral | |||
| TCR-L096Z | Human anti-pp65 (aa495-503) T cell receptor, pCDTCR1 | CMV | Human | NLVPMVATV | HLA-A*0201 | Lentiviral | ||
| TCR-L097Z | Human anti-pp65 (aa509-523) T cell receptor (Codon optimized), pCDTCR1 | CMV | Human | KYQEFFWDANDIYRI | HLA-DRB1*0101 | Lentiviral | ||
| TCR-L098Z | Human anti-pp65 (aa341-349) T cell receptor, pCDTCR1 | CMV | Human | QYDPVAALF | Lentiviral | |||
| TCR-L099Z | Human anti-pp65 (aa417-426) T cell receptor (Codon optimized and cysteine modified), pCDTCR1 | CMV | Human | TPRVTGGAM | HLA-B7 | Lentiviral | ||
| TCR-L100Z | Human anti-pp65 (aa265-275) T cell receptor (Codon optimized and cysteine modified), pCDTCR1 | CMV | Human | RPHERNGFTVL | HLA-B7 | Lentiviral | ||
| TCR-C212Z | Human anti-pp65 T cell receptor (RA14), pCDTCR1 | CMV | RA14 | Human | NLVPMVATV | HLA-A2 | Lentiviral | |
| TCR-C213Z | Human anti-pp65 T cell receptor (12), pCDTCR1 | CMV | 12 | Human | IPSINVHHY | HLA-B35 | Lentiviral | |
| TCR-C214Z | Human anti-pp65 T cell receptor (JG-9), pCDTCR1 | CMV | JG-9 | Human | NLVPMVATV | HLA-A*0201 | Lentiviral | |
| TCR-C215Z | Human anti-pp65 T cell receptor (JG-33), pCDTCR1 | CMV | JG-33 | Human | NLVPMVATV | HLA-A*0201 | Lentiviral | |
| TCR-C216Z | Human anti-pp65 T cell receptor (MD-19), pCDTCR1 | CMV | MD-19 | Human | YSEHPTFTSQY | HLA-A*0101 | Lentiviral | |
| TCR-C217Z | Human anti-pp65 T cell receptor (BF-33/BF-38), pCDTCR1 | CMV | BF-33/BF-38 | Human | IPSINVHHY | HLA-B*3501 | Lentiviral | |
| TCR-C218Z | Human anti-pp65 T cell receptor (Codon optimized), pCDTCR1 | CMV | Human | NLVPMVATV | HLA-A2.1 | Lentiviral | ||
| TCR-C219Z | Human anti-pp65 T cell receptor (C7), pCDTCR1 | CMV | C7 | Human | NLVPMVATV | HLA-A2 | Lentiviral |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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