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Renal cell carcinoma

Overview

Renal cell carcinoma (RCC, also called hypernephroma, Grawitz tumor, renal adenocarcinoma) is a kidney cancer that arise from the lining of the renal tubule, a portion of the very small tubes in the kidney for filtering the blood and producing the urine. RCC accounts for approximately 90-95% of all kidney cancer cases, which is the most common type of kidney cancer in adults.

Sign and symptom

RCC may keep its clinically mysterious by hiding the symptoms, therefore most patients have developed advanced disease when it is diagnosed. Only 10-15% of patients present the classic triad of flank pain on the side of the body between hip and ribs, hematuria which has red blood cells present in the urine, and flank mass. Other signs and symptoms include weight loss and/or loss of appetite, recurrent fevers, hypertension due to the secretion of renin by the tumor, hypercalcemia, night sweats, malaise and a varicocele which usually occurs at left side caused by the obstruction of the testicular vein.

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