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CellRapeutics™ Leukopak from Human Immunodeficiency Virus HIV Donor (XS-0426-XU245)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak is collected via leukapheresis from HIV-positive donors, providing an extensive reservoir of peripheral blood mononuclear cells for virological and immunological research. The specimen includes the total T-cell compartment, monocytes harboring latent viral DNA, and B cells with chronic activation profiles. It is a fundamental resource for investigating the mechanisms of HIV latency, immune reconstitution, and the discovery of novel "shock and kill" therapeutic strategies.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Human Immunodeficiency Virus HIV Donor
  • Cat. No.
  • XS-0426-XU245
  • Donor Age
  • Young Adult, Middle-Aged
  • Donor Health
  • Confirmed HIV-positive status. The immune population reflects chronic viral-host dynamics, often showing skewed CD4/CD8 ratios and characteristic markers of cellular exhaustion or persistent activation.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Acid Citrate Dextrose, specialized to maximize the recovery of CD4+ subsets and ensure the stability of the proviral reservoir within cells.
  • Additional Donor Information
  • Each lot features a Leukopak from HIV-positive donors. Profiles include CD4+ counts, viral load history, and ART adherence, providing high-volume cells for studying viral reservoirs and cellular immunotherapy.
  • Clinical Profile
  • Current CD4+ count, viral load status, and duration of ART.

Additional Information

  • Medication History
  • Available upon request. Comprehensive history of Antiretroviral Therapy, CD4+ counts, and viral load suppression records.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Human Immunodeficiency Virus HIV Donor, Leukopak, Human Immunodeficiency Virus HIV

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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