CellRapeutics™ Leukopak from Rheumatoid Arthritis Donor (XS-0426-XU261)

Name: CellRapeutics™ Leukopak from Rheumatoid Arthritis Donor
SKU: XS-0426-XU261
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak is harvested from donors meeting the specific criteria for Rheumatoid Arthritis. The specimen provides an expansive reservoir of peripheral blood mononuclear cells characterized by the systemic expansion of proinflammatory Th17 and Th1 subsets, alongside autoreactive B-cell clones. It is an ideal substrate for large-scale studies concerning the loss of self-tolerance, the signaling pathways of citrullinated protein recognition, and the development of targeted therapies for chronic synovial inflammation.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Rheumatoid Arthritis Donor

Cat. No.
XS-0426-XU261

Donor Age
Middle-Aged, Senior

Donor Health
Clinically diagnosed with systemic Rheumatoid Arthritis. Leukocytes reflect chronic synovial autoimmunity, featuring expanded pro-inflammatory monocyte subsets and autoreactive lymphocytes associated with RF or anti-CCP production.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, optimized to prevent platelet-leukocyte aggregate formation and maintain the suppressive function of Tregs.

Additional Donor Information
Each lot features a Leukopak from donors with confirmed RA. Profiles include RF and anti-CCP status alongside DAS28 scores, supporting the study of synovial-homing lymphocytes and systemic immune dysregulation.

Clinical Profile
History of diagnosis, RF and anti-CCP antibody status, current DAS28 score, and history of DMARDs or biologic therapies.

Additional Information

Medication History
Available upon request. Includes history of methotrexate, corticosteroids, and a range of biological or targeted synthetic DMARDs.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Rheumatoid Arthritis Donor, Leukopak, Rheumatoid Arthritis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.