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Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| XS-0922-ZP1079 | Anti-EGFRvIII (#2173) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | #2173 | Humanized | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0922-ZP1344 | Anti-EGFRvIII (C2173) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | C2173 | Humanized | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0922-ZP1345 | Anti-EGFRvIII (GCT02) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | GCT02 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0922-ZP1388 | Anti-EGFRvIII (139) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 139 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-1022-LX659 | Anti-EGFRvIII (X10X491) h(CD28-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X491 | Mouse | scFv-CD28-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX660 | Anti-EGFRvIII (X10X492) h(CD28-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X492 | Mouse | scFv-CD28-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX1313 | Anti-EGFRvIII (X10X491) h(41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X491 | Mouse | scFv-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX1314 | Anti-EGFRvIII (X10X492) h(41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X492 | Mouse | scFv-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX1315 | Anti-EGFRvIII (X10X493) h(41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X493 | Mouse | scFv-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX1967 | Anti-EGFRvIII (X10X491) h(CD28-41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X491 | Mouse | scFv-CD28-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX1968 | Anti-EGFRvIII (X10X492) h(CD28-41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X492 | Mouse | scFv-CD28-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX1969 | Anti-EGFRvIII (X10X493) h(CD28-41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X493 | Mouse | scFv-CD28-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1122-YF329 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-329), pCDCAR1 | Human | XW-329 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF330 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-330), pCDCAR1 | Human | XW-330 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF331 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-331), pCDCAR1 | Human | XW-331 | Human | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF332 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-332), pCDCAR1 | Mouse | XW-332 | Rat | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF333 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-333), pCDCAR1 | Human | XW-333 | Humanized | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF334 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-334), pCDCAR1 | Human | XW-334 | Humanized | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF335 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-335), pCDCAR1 | Human | XW-335 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF336 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-336), pCDCAR1 | Human | XW-336 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-0823-LX39 | Anti-hEGFRvIII (139) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector | Human | 139 | Adenoviral vectors |
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