Nef

The HIV Nef protein is a multifunctional virulence factor that perturbs intracellular membranes and signalling and is secreted into exosomes. While Nef-containing exosomes have a distinct proteomic profile, no comprehensive analysis of their miRNA cargo has been carried out. Since Nef functions as a viral suppressor of RNA interference and disturbs the distribution of RNA-induced silencing complex proteins between cells and exosomes, we hypothesized that it might also affect the export of miRNAs into exosomes.

Associated Disease
  • HIV-1 infection

TCR Vector Products Product list:

Catalog Target Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Vector
Type
Epitope Format HLA Data
sheet
Price
TCR-C168Z Nef HIV-1 H27-14 Human ~8kb Lentiviral RYPLTFGWCF Non-modified HLA-A24 Inquiry
TCR-C169Z Nef HIV-1 Human ~8kb Lentiviral PDWQNYTPGPG Non-modified HLA-A24 Inquiry
TCR-C170Z Nef HIV-1 Human ~8kb Lentiviral RPMTYKGAL Non-modified HLA-B0702 Inquiry
TCR-C171Z Nef HIV-1 C1-28 Human ~8kb Lentiviral RYPLTFGWCF Non-modified HLA-A24 Inquiry
TCR-C172Z Nef HIV-1 T36-5 Human ~8kb Lentiviral RFPLTFGWCF Non-modified HLA-A24 Inquiry
TCR-C458 Nef HIV-1 CB-C198 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C459 Nef HIV-1 CB-C199 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C460 Nef HIV-1 CB-C200 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C461 Nef HIV-1 CB-C201 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C462 Nef HIV-1 CB-C202 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C463 Nef HIV-1 CB-C203 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C464 Nef HIV-1 CB-C204 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C465 Nef HIV-1 CB-C205 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C466 Nef HIV-1 CB-C206 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C467 Nef HIV-1 CB-C207 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C468 Nef HIV-1 CB-C208 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C469 Nef HIV-1 CB-C209 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C470 Nef HIV-1 CB-C210 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C471 Nef HIV-1 CB-C211 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C472 Nef HIV-1 CB-C212 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C473 Nef HIV-1 CB-C213 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C474 Nef HIV-1 CB-C214 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C475 Nef HIV-1 CB-C215 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C476 Nef HIV-1 CB-C216 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C477 Nef HIV-1 CB-C217 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C478 Nef HIV-1 CB-C218 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C479 Nef HIV-1 CB-C219 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C480 Nef HIV-1 CB-C220 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C481 Nef HIV-1 CB-C221 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C482 Nef HIV-1 CB-C222 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C483 Nef HIV-1 CB-C223 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C484 Nef HIV-1 CB-C224 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C485 Nef HIV-1 CB-C225 Human ~8kb Lentiviral vector RYPLTFGWCF Non-modified TCR HLA-A*24:02 Inquiry
TCR-C486 Nef HIV-1 CB-C226 Human ~8kb Lentiviral vector RYPLTFGW Non-modified TCR HLA-A*24:02 Inquiry
TCR-C487 Nef HIV-1 CB-C227 Human ~8kb Lentiviral vector RYPLTFGW Non-modified TCR HLA-A*24:02 Inquiry
TCR-C488 Nef HIV-1 CB-C228 Human ~8kb Lentiviral vector RYPLTFGW Non-modified TCR HLA-A*24:02 Inquiry
TCR-C489 Nef HIV-1 CB-C229 Human ~8kb Lentiviral vector RYPLTFGW Non-modified TCR HLA-A*24:02 Inquiry
TCR-C490 Nef HIV-1 CB-C230 Human ~8kb Lentiviral vector RYPLTFGW Non-modified TCR HLA-A*24:02 Inquiry
TCR-C491 Nef HIV-1 CB-C231 Human ~8kb Lentiviral vector RYPLTFGW Non-modified TCR HLA-A*24:02 Inquiry
TCR-C492 Nef HIV-1 CB-C232 Human ~8kb Lentiviral vector RYPLTFGW Non-modified TCR HLA-A*24:02 Inquiry
TCR-L075Z nef HIV Human 8kb Lentiviral KAAVDLSHFL Non-modified HLA-C*0802 Inquiry
TCR-L076 nef HIV Human 6700-8070bp retroviral vector KAAVDLSHFL Non-modified TCR HLA-C*0802 Inquiry
TCR-L325 Nef HIV-l HIV-B8-FL8 Human ~8kb Lentiviral FLKEKGGL Non-modified HLA-B8 Inquiry
TCR-L328 Nef HIV-l HIV-B8-FL8-2 Human ~8kb Lentiviral FLKEKGGL Non-modified HLA-B8 Inquiry
TCR-L333 Nef HIV-l HIV-B60-KL9 Human ~8kb Lentiviral KEKGGLEGL Non-modified HLA-B60 Inquiry
TCR-L335 Nef HIV-l HIV-A3-QK10 Human ~8kb Lentiviral QVPLRPMTYK Non-modified HLA-A3/A11 Inquiry
TCR-L336 Nef HIV-l HIV-A3-QK10-2 Human ~8kb Lentiviral QVPLRPMTYK Non-modified HLA-A3/A11 Inquiry
TCR-L337 Nef HIV-l HIV-A3-QK10-3 Human ~8kb Lentiviral QVPLRPMTYK Non-modified HLA-A3/A11 Inquiry
TCR-L338 Nef HIV-l HIV-A3-QK10-4 Human ~8kb Lentiviral QVPLRPMTYK Non-modified HLA-A3/A11 Inquiry
TCR-L339 Nef HIV-l HIV-A3-QK10-5 Human ~8kb Lentiviral QVPLRPMTYK Non-modified HLA-A3/A11 Inquiry
TCR-L340 Nef HIV-l HIV-A3-QK10-6 Human ~8kb Lentiviral QVPLRPMTYK Non-modified HLA-A3 Inquiry
TCR-L341 Nef HIV-l HIV-A3-QK10-7 Human ~8kb Lentiviral QVPLRPMTYK Non-modified HLA-A3 Inquiry

TCR Viral Particles Product list:

Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Packaging
System
Epitope Format Titer Data
sheet
Price
VP-TCR-C314 HIV-1 H27-14 Human Lentivirus RYPLTFGWCF Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C315 HIV-1 Human Lentivirus PDWQNYTPGPG Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C316 HIV-1 Human Lentivirus RPMTYKGAL Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C317 HIV-1 C1-28 Human Lentivirus RYPLTFGWCF Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C318 HIV-1 T36-5 Human Lentivirus RFPLTFGWCF Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C319 HIV-l HIV-B8-FL8 Human Lentivirus FLKEKGGL Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C320 HIV-l HIV-B8-FL8-2 Human Lentivirus FLKEKGGL Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C321 HIV-l HIV-B60-KL9 Human Lentivirus KEKGGLEGL Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C322 HIV-l HIV-A3-QK10 Human Lentivirus QVPLRPMTYK Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C323 HIV-l HIV-A3-QK10-2 Human Lentivirus QVPLRPMTYK Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C324 HIV-l HIV-A3-QK10-3 Human Lentivirus QVPLRPMTYK Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C325 HIV-l HIV-A3-QK10-4 Human Lentivirus QVPLRPMTYK Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C326 HIV-l HIV-A3-QK10-5 Human Lentivirus QVPLRPMTYK Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C327 HIV-l HIV-A3-QK10-6 Human Lentivirus QVPLRPMTYK Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C328 HIV-l HIV-A3-QK10-7 Human Lentivirus QVPLRPMTYK Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C329 HIV Human Lentivirus KAAVDLSHFL Non-modified TCR > 10⁷ IFU/ml Inquiry
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