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The HIV Nef protein is a multifunctional virulence factor that perturbs intracellular membranes and signalling and is secreted into exosomes. While Nef-containing exosomes have a distinct proteomic profile, no comprehensive analysis of their miRNA cargo has been carried out. Since Nef functions as a viral suppressor of RNA interference and disturbs the distribution of RNA-induced silencing complex proteins between cells and exosomes, we hypothesized that it might also affect the export of miRNAs into exosomes.
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| CAT | Product Name | Target Species | TCR Clone | Host Species | Epitope | Allele | Vector Type | Inquiry & Datasheet |
| TCR-C458 | Human anti-Nef T cell receptor (CB-C198), pCDTCR1 | HIV-1 | CB-C198 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C459 | Human anti-Nef T cell receptor (CB-C199), pCDTCR1 | HIV-1 | CB-C199 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C460 | Human anti-Nef T cell receptor (CB-C200), pCDTCR1 | HIV-1 | CB-C200 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C461 | Human anti-Nef T cell receptor (CB-C201), pCDTCR1 | HIV-1 | CB-C201 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C462 | Human anti-Nef T cell receptor (CB-C202), pCDTCR1 | HIV-1 | CB-C202 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C463 | Human anti-Nef T cell receptor (CB-C203), pCDTCR1 | HIV-1 | CB-C203 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C464 | Human anti-Nef T cell receptor (CB-C204), pCDTCR1 | HIV-1 | CB-C204 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C465 | Human anti-Nef T cell receptor (CB-C205), pCDTCR1 | HIV-1 | CB-C205 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C466 | Human anti-Nef T cell receptor (CB-C206), pCDTCR1 | HIV-1 | CB-C206 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C467 | Human anti-Nef T cell receptor (CB-C207), pCDTCR1 | HIV-1 | CB-C207 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C468 | Human anti-Nef T cell receptor (CB-C208), pCDTCR1 | HIV-1 | CB-C208 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C469 | Human anti-Nef T cell receptor (CB-C209), pCDTCR1 | HIV-1 | CB-C209 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C470 | Human anti-Nef T cell receptor (CB-C210), pCDTCR1 | HIV-1 | CB-C210 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C471 | Human anti-Nef T cell receptor (CB-C211), pCDTCR1 | HIV-1 | CB-C211 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C472 | Human anti-Nef T cell receptor (CB-C212), pCDTCR1 | HIV-1 | CB-C212 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C473 | Human anti-Nef T cell receptor (CB-C213), pCDTCR1 | HIV-1 | CB-C213 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C474 | Human anti-Nef T cell receptor (CB-C214), pCDTCR1 | HIV-1 | CB-C214 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C475 | Human anti-Nef T cell receptor (CB-C215), pCDTCR1 | HIV-1 | CB-C215 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C476 | Human anti-Nef T cell receptor (CB-C216), pCDTCR1 | HIV-1 | CB-C216 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector | |
| TCR-C477 | Human anti-Nef T cell receptor (CB-C217), pCDTCR1 | HIV-1 | CB-C217 | Human | RYPLTFGWCF | HLA-A*24:02 | Lentiviral vector |
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