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Nef

The HIV Nef protein is a multifunctional virulence factor that perturbs intracellular membranes and signalling and is secreted into exosomes. While Nef-containing exosomes have a distinct proteomic profile, no comprehensive analysis of their miRNA cargo has been carried out. Since Nef functions as a viral suppressor of RNA interference and disturbs the distribution of RNA-induced silencing complex proteins between cells and exosomes, we hypothesized that it might also affect the export of miRNAs into exosomes.

Associated Disease
  • HIV-1 infection
  • TCR Vector Products
  • TCR Viral Particles
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  • HLA:
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CAT Product Name Target SpeciesTCR CloneTCR Host AnimalEpitopeHLAVector Type Inquiry & Datasheet
TCR-C458 Human anti-Nef T cell receptor (CB-C198), pCDTCR1 HIV-1 CB-C198 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C459 Human anti-Nef T cell receptor (CB-C199), pCDTCR1 HIV-1 CB-C199 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C460 Human anti-Nef T cell receptor (CB-C200), pCDTCR1 HIV-1 CB-C200 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C461 Human anti-Nef T cell receptor (CB-C201), pCDTCR1 HIV-1 CB-C201 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C462 Human anti-Nef T cell receptor (CB-C202), pCDTCR1 HIV-1 CB-C202 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C463 Human anti-Nef T cell receptor (CB-C203), pCDTCR1 HIV-1 CB-C203 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C464 Human anti-Nef T cell receptor (CB-C204), pCDTCR1 HIV-1 CB-C204 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C465 Human anti-Nef T cell receptor (CB-C205), pCDTCR1 HIV-1 CB-C205 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C466 Human anti-Nef T cell receptor (CB-C206), pCDTCR1 HIV-1 CB-C206 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C467 Human anti-Nef T cell receptor (CB-C207), pCDTCR1 HIV-1 CB-C207 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C468 Human anti-Nef T cell receptor (CB-C208), pCDTCR1 HIV-1 CB-C208 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C469 Human anti-Nef T cell receptor (CB-C209), pCDTCR1 HIV-1 CB-C209 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C470 Human anti-Nef T cell receptor (CB-C210), pCDTCR1 HIV-1 CB-C210 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C471 Human anti-Nef T cell receptor (CB-C211), pCDTCR1 HIV-1 CB-C211 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C472 Human anti-Nef T cell receptor (CB-C212), pCDTCR1 HIV-1 CB-C212 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C473 Human anti-Nef T cell receptor (CB-C213), pCDTCR1 HIV-1 CB-C213 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C474 Human anti-Nef T cell receptor (CB-C214), pCDTCR1 HIV-1 CB-C214 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C475 Human anti-Nef T cell receptor (CB-C215), pCDTCR1 HIV-1 CB-C215 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C476 Human anti-Nef T cell receptor (CB-C216), pCDTCR1 HIV-1 CB-C216 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C477 Human anti-Nef T cell receptor (CB-C217), pCDTCR1 HIV-1 CB-C217 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C478 Human anti-Nef T cell receptor (CB-C218), pCDTCR1 HIV-1 CB-C218 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C479 Human anti-Nef T cell receptor (CB-C219), pCDTCR1 HIV-1 CB-C219 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C480 Human anti-Nef T cell receptor (CB-C220), pCDTCR1 HIV-1 CB-C220 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C481 Human anti-Nef T cell receptor (CB-C221), pCDTCR1 HIV-1 CB-C221 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C482 Human anti-Nef T cell receptor (CB-C222), pCDTCR1 HIV-1 CB-C222 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C483 Human anti-Nef T cell receptor (CB-C223), pCDTCR1 HIV-1 CB-C223 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C484 Human anti-Nef T cell receptor (CB-C224), pCDTCR1 HIV-1 CB-C224 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C485 Human anti-Nef T cell receptor (CB-C225), pCDTCR1 HIV-1 CB-C225 Human RYPLTFGWCF HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C486 Human anti-Nef T cell receptor (CB-C226), pCDTCR1 HIV-1 CB-C226 Human RYPLTFGW HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C487 Human anti-Nef T cell receptor (CB-C227), pCDTCR1 HIV-1 CB-C227 Human RYPLTFGW HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C488 Human anti-Nef T cell receptor (CB-C228), pCDTCR1 HIV-1 CB-C228 Human RYPLTFGW HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C489 Human anti-Nef T cell receptor (CB-C229), pCDTCR1 HIV-1 CB-C229 Human RYPLTFGW HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C490 Human anti-Nef T cell receptor (CB-C230), pCDTCR1 HIV-1 CB-C230 Human RYPLTFGW HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C491 Human anti-Nef T cell receptor (CB-C231), pCDTCR1 HIV-1 CB-C231 Human RYPLTFGW HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-C492 Human anti-Nef T cell receptor (CB-C232), pCDTCR1 HIV-1 CB-C232 Human RYPLTFGW HLA-A*24:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0725 Human anti-nef T cell receptor ((H27-14)-1), pCDTCR1 HIV1 H27-14 Human RFPLTFGWCF HLA-A24 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0726 Human anti-nef T cell receptor ((H27-14)-2), pCDTCR1 HIV1 H27-14 Human RYPLTFGWCF HLA-A24 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0727 Human anti-nef T cell receptor ((H27-14)-3), pCDTCR1 HIV1 H27-14 Human RYPLTLGWCF HLA-A24 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0728 Human anti-nef T cell receptor (I30-1), pCDTCR1 HIV1 I30-1 Human NYTPGPGIRY HLA-A24 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0729 Human anti-nef T cell receptor (S19-2), pCDTCR1 HIV1 S19-2 Human RYPLTFGWCF HLA-A*2402 Lentiviral vector   Add to Cart   Datasheet

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