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Anti-Art v 1 [25-36] TCR, pMSGV1 (TCR-L064)

The vector of anti-major mugwort (Artemisia vulgaris) pollen allergen Art v 1 T cell receptor (TCR) is constructed for the engineering of T cell to target Mugwort major mugwort (Artemisia vulgaris) pollen allergen Art v 1. The T cells are genetically modified through transduction with a retroviral vector expressing major mugwort (Artemisia vulgaris) pollen allergen Art v 1-specific T cell receptor. And the vector product was designed for tolerance induction therapies in individuals with allergic and other immune-mediated diseases.

Details

  • Target
  • major mugwort (Artemisia vulgaris) pollen allergen Art v 1
  • Target Species
  • Mugwort
  • Epitope
  • Art v 1[25-36]
  • Format
  • Non-modified TCR
  • HLA
  • HLA-DR1
  • Targeting Diseases
  • Allergy
  • Vector Name
  • pMSGV1
  • Vector Length
  • 6700-8070bp
  • Vector Type
  • retroviral vector
  • Antibody Host
  • Human

Target

  • Gene Name
  • Major pollen allergen Art v 1
  • Official Symbol
  • Art v 1
  • Synonyms
  • MLANA; Melan-A; Antigen LB39-AA; Antigen SK29-AA; Melanoma Antigen Recognized By T-Cells 1; MART1; MART-1; Protein Melan-A; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Melanoma
  • Introduction
  • Art v 1, the major allergen of mugwort pollen, is a modular glycoprotein with a defensin-like and a hydroxyproline-rich domain.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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