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Anti-C85H168O4 T cell receptor (Clone 28 C58L), pCDTCR1 (TCR-YC0291)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-C85H168O4 T cell receptor (TCR) is constructed for the engineering of T cell to target C85H168O4 ((2R)-2-[(1R)-1-hydroxy-16-{(1R,2S)-2-[(17R,18R)-17-methoxy-18-methylhexatriacontyl]cyclopropyl}hexadecyl]hexacosanoic acid) restricted by human CD1b. The T cells are genetically modified through transduction with a lentiviral vector expressing C85H168O4-specific T cell receptor.

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Details

  • Target
  • C85H168O4
  • Target Species
  • Mycobacterium tuberculosis
  • Epitope
  • (2R)-2-[(1R)-1-hydroxy-16-{(1R,2S)-2-[(17R,18R)-17-methoxy-18-methylhexatriacontyl]cyclopropyl}hexadecyl]hexacosanoic acid
  • Format
  • Non-Modified TCR
  • Allele
  • human CD1b
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • clone 28 C58L
  • Host Species
  • Human

Target

  • Introduction
  • A synthetic chiral mycolic acid analogue comprising 3-hydroxypropanoic acid having a tetracosanyl group at position 2 and a further long-chain alkyl group containing cyclopropyl, methoxy and methyl functions attached at position 3.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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