Anti-CD34 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1235-YY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CD34 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CD34

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
947

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1235-YY	CBYY-C3231	Rabbit	Human	IgG	Recombinant Human CD34 protein. This antibody was obtained from a rabbit immunized with purified, recombinant Human CD34
DMAb-1123-YY	CBYY-C1323	Mouse	Human	IgG2b
DMAb-1124-YY	CBYY-C1324	Mouse	Human	IgG2b
DMAb-1125-YY	CBYY-C1325	Mouse	Human	IgG1	KG1 human acute myelogenous cells
DMAb-1126-YY	CBYY-C1326	Mouse	Human	IgG2a
DMAb-1127-YY	CBYY-C1327	Mouse			CD34 (NP_001764, 32aa-141aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD
DMAb-1128-YY	CBYY-C1328	Mouse	Human	IgG1, κ
DMAb-1129-YY	CBYY-C1329	Mouse	Human	IgG1	KG1 human acute myelogenous cells
DMAb-1130-YY	CBYY-C1330	Mouse	Human	IgG1	Blast cells of a chronic myeloid leukemia patient
DMAb-1109-YY	CBYY-C0709	Mouse	Human	IgG1, κ
DMAb-1106-YY	CBYY-C0602	Mouse	Human	IgG3, κ	Human KG-1a tumor cells
DMAb-1100-YY	CBYY-C0559	Rat	Mouse	IgG2a	Mouse myeloma cell line NS0-derived recombinant mouse CD34, Thr35-Thr287, Accession # Q64314
DMAb-1103-YY	CBYY-C0568	Mouse	Human	IgG2b	Partial recombinant human CD34 protein (aa32-290)
DMAb-1090-YY	CBYY-C0390	Mouse	Human	IgG2b, κ	Human CD34
DMAb-1083-YY	CBYY-C0328	Mouse	Human	IgG2a, κ
DMAb-1084-YY	CBYY-C0329	Mouse	Human	IgG1, κ
DMAb-1085-YY	CBYY-C0346	Mouse	Human	IgG1	Human T lymphocytes
DMAb-0138-CN	MEC14.7	Rat	Mouse	IgG2a, κ	Full length protein corresponding to Mouse CD34. Murine transformed endothelioma cell line t-end

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CD34 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1235-YY)

Specifications

Target

Customer Reviews and Q&As

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