Anti-CD9 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0266-CN)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CD9 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CD9

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
493874

UniProt ID
P40239

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0266-CN	10B2131	Mouse		IgG1	Crude pellet of thymocyte-grown feline immunodefficieny virus
DMAb-0275-WJ	EM-04	Rat	Mouse	IgG1
DMAb-0277-WJ	HI9a	Mouse	Human	IgG1
DMAb-0278-WJ	IVA50	Mouse	Bovine	IgG2	Bovine thrombocytes
DMAb-0279-WJ	JF9	Rat	Mouse	IgG2b
DMAb-0280-WJ	KMC8	Rat	Mouse	IgG2a, κ
DMAb-0281-WJ	ALB6	Mouse	Human	IgG1	Human bone marrow malignant cells from acute non-T, non-B leukemia
DMAb-0304-CQ	MEM-61	Mouse	Human	IgG1	Pre-B cell line NALM-6
DMAb-0306-CQ	MM2/57	Mouse		IgG2b, κ	A peptide made to the amino acid region CD9
DMAb-0307-CQ	P1/33/2	Mouse	Human	IgG1	Acute lymphoblastic leukaemia cells
DMAb-0308-CQ	SN4	Mouse	Human	IgG1	The immunogen was CD9
DMAb-0310-CQ	SN4 C3-3A2	Mouse	Human	IgG1
DMAb-0312-CQ	MF1	Rat	Mouse	IgG
DMAb-0317-CQ	TS9	Mouse	Human	IgG1
DMAb-0318-CQ	A100-4	Mouse		IgG2a	Human prostate carcinoma cell line (PC3) derived exosomes

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CD9 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0266-CN)

Specifications

Target

Customer Reviews and Q&As

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