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Anti-CSF1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-3954-FY)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CSF1 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

  • Target
  • CSF1
  • Vector Name
  • pVAX1
  • Vector Description
  • pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
  • Vector Promoter
  • CMV
  • Vector Tag or Fusion
  • Untagged
  • Delivery Method
  • Transfection
  • Cloning Method
  • Restriction Enzyme ⁄ MCS
  • Constitutive or Inducible System
  • Constitutive
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.
  • Background
  • DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

  • Entrez Gene ID
  • 1435
Sub CAT. DMAb Clone DMAb Host Target Species DMAb Isotype DMAb Immunogen  
DMAb-3954-FY CBFYC-2269 Mouse Human IgG1
DMAb-3955-FY CBFYC-2270 Mouse Human IgG1, k CSF1 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: EEVSEYCSHM IGSGHLQSLQ RLIDSQMETS CQITFEFVDQ EQLKDPVCYL KKAFLLVQDI MEDTMRFRDN TPNAIAIVQL QELSLRLKSC FTKDYEEHDK
DMAb-3956-FY CBFYC-2271 Mouse Human IgG2a Purified recombinant human M-CSF (rhM-CSF)
DMAb-3675-FY 4C9G2 Mouse Human Recombinant fragment of human CSF1R (AA: 20-152) expressed in E. Coli
DMAb-3676-FY CBFYM-0034 Rat Human IgG2a, k
DMAb-3677-FY CBFYM-0100 Mouse Human IgG2a E. coli-derived recombinant human M-CSF
DMAb-3678-FY CBFYM-0136 Mouse Human IgG1 Human monocytes
DMAb-3679-FY CBFYM-0153 Rat Mouse IgG2b Mouse myeloma cell line NS0-derived recombinant mouse M-CSF R, Ala20-Ser511
DMAb-3680-FY CBFYM-0184 Rat Mouse IgG1
DMAb-3681-FY CBFYM-0247 Rat Human IgG2a
DMAb-3682-FY CBFYM-0256 Rat Mouse IgG2b
DMAb-3683-FY CBFYM-0271 Mouse Human IgG1
DMAb-3684-FY CBFYM-0276 Rabbit Human IgG
DMAb-3685-FY CBFYM-0324 Mouse Rat IgG2a, k
DMAb-3686-FY CBFYM-0334 Mouse Chicken IgG1 Chicken peripheral blood mononuclear cell leukocytes
DMAb-3687-FY CBFYM-0351 Mouse Human IgG1 Macrophage L1 protein Calprotectin antibody was raised in mouse using affinity purified monocyte membrane preparation
DMAb-3688-FY CBFYM-0402 Rat Mouse IgG2a
DMAb-3689-FY CBFYM-0469 Mouse Human IgG1
DMAb-3690-FY CBFYM-0530 Mouse Human IgG1
DMAb-3691-FY CBFYM-1027 Mouse Human IgG2b Human recombinant protein fragment corresponding to amino acids 223-496 of human CSF1 (NP_000748) produced in E.coli
DMAb-3692-FY CBFYM-1028 Mouse Human IgG1 Human CSF1 expressed in E. Coli
DMAb-3693-FY CBFYM-1029 Mouse Human IgG1 Recombinant human MCP-3 (Macrophage Chemoattractant Protein-3)
DMAb-3694-FY CBFYM-1030 Mouse Human IgG2a Recombint human MCAF
DMAb-3695-FY CBFYM-1031 Mouse Human IgG1
DMAb-3696-FY CBFYM-1032 Rat Human IgG1 V-ras-transformed rat NRK cells expressing transduced human CSF-1R
DMAb-3697-FY CBFYM-1033 Mouse Human IgM, k Human sebocytes
DMAb-3698-FY CBFYM-1034 Mouse Human IgG3, k Human M-CSF
DMAb-3699-FY CBFYM-1035 Rat Mouse IgG2b E. coli-derived recombinant mouse M-CSF, Lys33-Glu262
DMAb-3700-FY CBFYM-1036 Rabbit Mouse IgG Synthetic peptide derived from N-terminus of Mouse F4/80 protein
DMAb-3701-FY CBFYM-1037 Mouse Rat IgG1 E. coli-derived recombinant rat M-CSF, Glu33-Glu261
DMAb-3702-FY CBFYM-1038 Mouse Rat
DMAb-3740CQ CBXC-2007 Mouse IgG1 Recombinant protein corresponding to amino acids 223-496 of human CSF1(NP_000748) produced in E. coli
DMAb-3741CQ CBXC-2497 Mouse IgG1 Recombinant protein corresponding to amino acids 223-496 of human CSF1(NP_000748) produced in E. coli
DMAb-3742CQ CBXC-3096 Mouse IgG2b Recombinant protein corresponding to amino acids 223-496 of human CSF1(NP_000748) produced in E. coli

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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