Anti-CSF1R DNA-encoded mAb (DMAb), pVAX1 (DMAb-3707CQ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CSF1R DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CSF1R

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
1436

UniProt ID
P07333

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-3707CQ	CBXC-0582	Rat		IgG1, κ
DMAb-3730CQ	CBXC-2381	Rat		IgG1
DMAb-3703-FY	6B9H2	Mouse	Human	IgG2b	Recombinant fragment of human CSF1R (AA: 344-497) expressed in E. Coli
DMAb-3704-FY	CBFYM-0001	Mouse	Human	IgG1	Recombinant Human CSF1R/MCSF Receptor/CD115 Protein
DMAb-3705-FY	CBFYM-0234	Mouse	Human	IgG1	Recombinant protein corresponding to the extracellular domain of human macrophage colony stimulating factor receptor expressed in NSO cells
DMAb-3706-FY	CBFYM-0237	Rat	Mouse	IgG2a
DMAb-3707-FY	CBFYM-0780	Rat	Mouse	IgG2b	Recombinant protein corresponding to aa20-511 from mouse Macrophage Colony Stimulating Factor Receptor (P09581)
DMAb-3708-FY	CBFYM-1039	Mouse	Human	IgG1
DMAb-3709-FY	CBFYM-1040	Mouse	Human	IgG1
DMAb-3710-FY	CBFYM-1041	Rabbit	Human	IgG	Recombinant Human CSF1R/MCSF Receptor/CD115 protein
DMAb-3711-FY	CBFYM-1042	Mouse	Human	IgG1	Recombinant Human MCSFR/CD115 protein
DMAb-3712-FY	CBFYM-1043	Mouse	Human	IgG1	Recombinant human MCSFR/CD115 protein
DMAb-3713-FY	CBFYM-1044	Rabbit	Human	IgG	Recombinant human M-CSFR protein
DMAb-3714-FY	CBFYM-1045	Mouse	Human	IgG2a, k	Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
DMAb-3715-FY	CBFYM-1046	Rat	Human	IgG1
DMAb-3957-FY	CBFYC-0245	Rat	Human	IgG2a, k
DMAb-3958-FY	CBFYC-2272	Mouse	Human		Recombinant protein corresponding to aa344-497 from human CSF1R expressed in E. coli
DMAb-3959-FY	CBFYC-2273	Mouse	Human	IgG1, IgM, k	This CSF1R Monoclonal antibody was raised using purified His-tagged recombinant human CSF1R
DMAb-3960-FY	CBFYC-2274	Rabbit	Mouse	IgG	Recombinant Mouse CSF1R/MCSF Receptor/CD115 protein
DMAb-3961-FY	CBFYC-2275	Mouse	Human	IgG1, k	CSF1R (AAH47521, AA 21-120 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen type: GST fusion protein
DMAb-3962-FY	CBFYC-2276	Mouse	Human	IgG1, k	This CSF1R antibody is generated from a mouse immunized with a recombinant protein
DMAb-3963-FY	CBFYC-2277	Rat	Human	IgG1, k	Recognizes proteins of 130kD & 150kD, identified as immature (gp130c-fms) and mature (gp150c-fms) forms of human CD115.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CSF1R DNA-encoded mAb (DMAb), pVAX1 (DMAb-3707CQ)

Specifications

Target

Customer Reviews and Q&As

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