Anti-DDX58 DNA-encoded mAb (DMAb), pVAX1 (DMAb-398-YC)

Name: Anti-DDX58 DNA-encoded mAb (DMAb), pVAX1
SKU: DMAb-398-YC
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-DDX58 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
DDX58

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
23586

UniProt ID
O95786

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-398-YC	2M6F10	Mouse		IgG1, κ	A portion of amino acid 1-50 of human RIG-I was used. 31 PWFREEEVQYIQAEkNNkG 49
DMAb-399-YC	4G1B6	Mouse	Human	IgM	Recombinant fragment of human DDX58 (a.a 789-925) expressed in E. Coli
DMAb-400-YC	6C1	Mouse	Human	IgG2a	Full length human recombinant protein of human DDX58(NP_055129) produced in HEK293T cell.
DMAb-401-YC	7D5	Mouse	Human	IgG2b	Full length human recombinant protein of human DDX58(NP_055129) produced in HEK293T cell.
DMAb-402-YC	8D2	Mouse	Human	IgG1
DMAb-403-YC	9F1B20	Mouse	Human	IgG2a, κ	Partial DDX58 recombinant protein (1-228 a.a.) expressed in E. coli
DMAb-405-YC	Alme-1	Mouse		IgG1	Recombinant human RIG-I (a.a. 201-713)
DMAb-406-YC	35H2L48	Rabbit	Human	IgG
DMAb-408-YC	IMG2M6F10	Mouse	Human	IgG1, κ	Amino acids 1-50 of human RIG-I were used

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-DDX58 DNA-encoded mAb (DMAb), pVAX1 (DMAb-398-YC)

Specifications

Target

Customer Reviews and Q&As

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