Anti-DFFA DNA-encoded mAb (DMAb), pVAX1 (DMAb-440-YC)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-DFFA DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
DFFA

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
1676

UniProt ID
O00273

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-440-YC	11C13	Mouse	Human	IgG1	Purified, E.coli-derived recombinant human DFF45 (a.a.1-331; Accession # O00273)
DMAb-441-YC	13A252	Mouse	Human	IgG1	Recombinant protein corresponding to human DFF45-GST fusion protein
DMAb-442-YC	19/DFF45	Mouse	Human	IgG1	Human DFF45 (a.a.105-305)
DMAb-444-YC	6B8	Mouse	Human	IgG1	Recombinant human DFF45
DMAb-445-YC	1B10	Mouse	Human	IgG1	Recombinant protein expressed in E.coli corresponding to amino acids 1-331 of human DFF45
DMAb-446-YC	2262C2a	Mouse	Human	IgG1	Recombinant Human Dna Fragmentation Factor, 45 Kda, Alpha Polypeptide (Dffa)
DMAb-447-YC	3F12	Mouse	Human	IgG1	Full length human recombinant protein of human DFFA (NP_004392) produced in E. coli
DMAb-448-YC	5C4	Mouse	Human	IgG1	Full length human recombinant protein of human DFFA (NP_004392) produced in E. coli.
DMAb-449-YC	3A11	Mouse	Human	IgG2a, κ	DFFA (NP_004392.1, 231 a.a. ~ 331 a.a) partial recombinant protein with GST tag. The immunogen sequence: TSSDVALASH ILTALREKQA PELSLSSQDL ELVTKEDPKA LAVALNWDIK KTETVQEACE RELALRLQQT QSLHSLRSIS ASKASPPGDL QNPKRARQDP T

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-DFFA DNA-encoded mAb (DMAb), pVAX1 (DMAb-440-YC)

Specifications

Target

Customer Reviews and Q&As

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