Anti-ENO2 DNA-encoded mAb (DMAb), pVAX1 (DMAb-3419-FY)

Name: Anti-ENO2 DNA-encoded mAb (DMAb), pVAX1
SKU: DMAb-3419-FY
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-ENO2 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
ENO2

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
2026

UniProt ID
P09104

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-3419-FY	5E2	Mouse	Guinea Pig	IgG2a
DMAb-3421-FY	AT17D10	Mouse	Human	IgG2b, κ	Recombinant human NSE purified from E.coli. Immunogen type: Recombinant protein.
DMAb-3422-FY	BBS-NC-VI-H14	Mouse		IgG1	Purified Human gamma-gamma Enolase
DMAb-3423-FY	NSEP2	Mouse	Human	IgG1, κ	Ovalbumin-conjugated synthetic peptides corresponding to human NSE amino acid sequence: TGDQLGALYQDFVRD
DMAb-3463CQ	BA0108	Rabbit		IgG	Human NSE aa 200-350
DMAb-3464CQ	ENO2/1462	Mouse		IgG2b	Human NSE aa 416-433
DMAb-3465CQ	SPM347	Mouse	Human	IgG2b	Human NSE aa 416-433
DMAb-3466CQ	ENO2/1375	Mouse		IgG2b	Synthetic peptide within Human NSE aa 416-433
DMAb-3467CQ	BA0013	Rabbit	Human	IgG	Human REEP5 aa 150 to the C-terminus
DMAb-3468CQ	BA0239	Rabbit		IgG	Synthetic peptide from residues in human NSE
DMAb-3470CQ	37E4	Mouse		IgG1	Recombinant full length protein
DMAb-3471CQ	85F11	Mouse		IgG2a, κ	Recombinant full length protein
DMAb-3472CQ	BA0240	Rabbit		IgG	Synthetic peptide
DMAb-3473CQ	NSE-P1	Mouse	Human	IgG1	C terminal amino acids 416-433 of NSE

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-ENO2 DNA-encoded mAb (DMAb), pVAX1 (DMAb-3419-FY)

Specifications

Target

Customer Reviews and Q&As

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