Anti-HMHA1 (VLHDDLLEA) TCR, pMP71(TCR-L039)
The vector of anti-HA-1 T cell receptor (TCR) is constructed for the engineering of T cell to target HA-1. The T cells are genetically modified through transduction with a retroviral vector expressing HA-1-specific T cell receptor. And the vector product was designed for the treatment of hematological malignancies.
Details
Format
Codon optimized and cysteine modified TCR
Targeting Diseases
hematological malignancies
Vector Type
retroviral vector
Target
Gene Name
histocompatibility (minor) HA-1
Synonyms
HbsAg; HBV; Major surface antigen; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; HBV; HCC
Introduction
HMHA1 (Histocompatibility (Minor) HA-1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Rho GTPase cycle. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP19.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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Datasheet
