Anti-HSPA5 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1436-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-HSPA5 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
HSPA5

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
3309

UniProt ID
P11021

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0656-FY	6H4.2G7	Mouse	Human	IgG1
DMAb-0701-FY	1H11-1H7	Mouse			His-tagged human GRP78
DMAb-0491-LY	10C3	Mouse		IgG2a	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0492-LY	15B165	Mouse		IgG	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0493-LY	3C5-1A4	Mouse		IgG1, κ	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-3431CQ	3D2	Mouse	Human	IgG1, κ	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0495-LY	3G12-1G11	Mouse		IgG1, κ	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0497-LY	474421	Mouse	Human	IgG2b	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0498-LY	4E87	Mouse		IgG2a	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0499-LY	4E88	Mouse		IgG	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0500-LY	5K23	Rat	Mouse	IgG1, κ	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0501-LY	6H4-2G7	Mouse		IgG1	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0502-LY	C38	Mouse	Human	IgG2b, κ	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0503-LY	10C9	Mouse		IgG	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0504-LY	13k16	Mouse		IgG1	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0505-LY	42773	Mouse	Human	IgG1	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0506-LY	4E3	Mouse		IgG1	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0508-LY	76-E6	Rat		IgG1	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0509-LY	8G3	Mouse		IgG	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0510-LY	9E4-2A7-H6	Mouse		IgG1	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0511-LY	AT3D2	Mouse	Human	IgG1	Heat Shock Protein Family A (Hsp70) Member 5
DMAb-0512-LY	C9-9	Mouse		IgG1	Heat Shock Protein Family A (Hsp70) Member 5

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-HSPA5 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1436-FY)

Specifications

Target

Customer Reviews and Q&As

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