The AbTCR fuses an antigen-binding domain from anti-ITGB7 (hu504.32) antibody with the C- terminal signaling domain of a γδTCR. More specifically, the antigen-binding domain of our AbTCR is an antibody Fab fragment, and the cellular-activation domain of consists of portions of the δ and γ chains of a γδTCR. And the vector product is designed to facilitate T-cell cytotoxicity with low cytokine release and is used in Colorectal cancer.
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All services and products are only for lab research use, not for any clinical diagnosis or treatment.
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