Anti-KRT18 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1471-CQ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-KRT18 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
KRT18

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
3875

UniProt ID
P05783

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1472-CQ	Ks18.04	Mouse		IgG1	Cytoskeleton preparation of epidermal carcinoma cell line A431
DMAb-1473-CQ	DA7	Mouse	Human	IgG1, κ	Human breast cancer PMC 42 cells
DMAb-1474-CQ	DC10	Mouse	Human	IgG1	Human breast cancer PMC 42 cells
DMAb-1475-CQ	DE-K18	Mouse		IgG1, κ	Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431
DMAb-1476-CQ	KRT18/1190	Mouse		IgG1, κ	Recombinant human KRT18 protein
DMAb-1477-CQ	KRT18/834	Mouse	Human	IgG1	Recombinant Full length human KRT18 protein
DMAb-1478-CQ	KRT18/836	Mouse		IgG1	Recombinant human KRT18 protein
DMAb-1479-CQ	LC18N	Mouse	Human	IgG1	Synthetic pepide of N terminus of human keratin 18 (NH2-SFTTRSTFSC)
DMAb-1480-CQ	LDK18	Mouse		IgG1	Synthetic peptide of human keratin 18 (CSETNDTKVLRH-COOH)
DMAb-1481-CQ	RCK106	Mouse	Human	IgG1	Cytokeratins from the human bladder carcinoma cell line T24
DMAb-1482-CQ	RGE53	Mouse		IgG1	A cytoskeletal preparation of cells
DMAb-1483-CQ	SPM265	Mouse	Human	IgG1	PMC-42 human breast carcinoma cells
DMAb-1484-CQ	SPM510	Mouse	Human	IgG1, κ	Human breast cancer PMC 42 cells
DMAb-1486-CQ	M6	Mouse	Human	IgG2a	Keratin 18 (K18) fragments purified from human carcinomas
DMAb-1487-CQ	M30	Mouse	Human	IgG2b	Keratin 18 (K18) fragments purified from supernatant from human carcinoma cell line WiDr CCL218
DMAb-1490-CQ	B23.1	Mouse	Human	IgG1	PMC-42 human breast carcinoma cells
DMAb-1491-CQ	RM279	Rabbit	Human	IgG	A peptide corresponding to the N-terminus of human Cytokeratin 18
DMAb-0886-WJ	C-04	Mouse		IgG1	Cytoskeleton preparation of epidermal carcinoma cell line A431
DMAb-1473-CQ	DA7	Mouse	Human	IgG1, κ	Human breast cancer PMC 42 cells were used as immunogen to generate the Cytokeratin 18 (CK18) antibody
DMAb-1474-CQ	DC10	Mouse	Human	IgG1	Human breast cancer PMC 42 cells were used as immunogen to generate the Keratin 18 antibody
DMAb-0896-WJ	Ks 18.04	Mouse		IgG1	Human cytokeratin 18
DMAb-1480-CQ	LDK18	Mouse	Human	IgG1, κ
DMAb-0903-WJ	CK-18	Mouse		IgG1	The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines
DMAb-0905-WJ	CY90	Mouse	Human	IgG1	Tissue / cell preparation (human epidermal carcinoma and MCF-7 human breast cancer allcells)
DMAb-0907-WJ	DEK-18	Mouse		IgG1
DMAb-1478-CQ	KRT18/836	Mouse		IgG1	Recombinant human KRT18 protein
DMAb-0916-WJ	M9	Mouse		IgG1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-KRT18 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1471-CQ)

Specifications

Target

Customer Reviews and Q&As

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