Anti-KRT7 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0948-WJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-KRT7 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
KRT7

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
3855

UniProt ID
P08729

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0948-WJ	C-46	Mouse		IgG1	Cytoskeleton preparation of HeLa human cervix carcinoma cell line
DMAb-0953-WJ	KRT7/1499R	Rabbit	Human	IgG	Recombinant full-length human KRT7 protein
DMAb-0954-WJ	KRT7/760	Mouse	Human	IgG1	Recombinant full-length human KRT7 protein
DMAb-0956-WJ	KRT7/760 + OV-TL12/30	Mouse		IgG	Recombinant full-length human KRT7 protein (KRT7/760); OTN 11, ovarian carcinoma cell line (OV-TL12/30)
DMAb-0958-WJ	LP5K	Mouse	Human	IgG2b
DMAb-0961-WJ	CK-7	Mouse	Human	IgG1	Cytoskeletal preparation of the RT4 human bladder carcinoma cell line
DMAb-0964-WJ	KRT7/903	Mouse	Human	IgG1	Recombinant full-length human KRT7 protein
DMAb-0965-WJ	Ks7.18	Mouse		IgG1	Cytokeratin 7 antibody was raised in mouse using cytoskeletal proteins from cultured HeLa cells as the immunogen
DMAb-0967-WJ	LDS-68	Mouse	Human	IgG1	Cytoskeletal preparation of the RT4 human bladder carcinoma cell line
DMAb-0968-WJ	LP1K	Mouse		IgG1	Sonicated cytoskeleton fractions ( insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes
DMAb-0948-WJ	C-46	Mouse		IgG1	Cytoskeleton preparation of HeLa human cervix carcinoma cell line
DMAb-1507-CQ	K72.7	Mouse	Human	IgG1, κ	Semi-purified cytokeratin preparation
DMAb-1508-CQ	KRT7/1198	Mouse		IgG1	Recombinant Full length human KRT7 protein
DMAb-0953-WJ	KRT7/1499R	Rabbit	Human	IgG	Recombinant Full length human KRT7 protein
DMAb-0954-WJ	KRT7/760	Mouse	Human	IgG1	Recombinant Full length human KRT7 protein
DMAb-1511-CQ	LdS 23	Mouse	Human	IgG1	Cytoskeletons of the human urothelial RT4 cell line
DMAb-1512-CQ	OV-TL12/30	Mouse	Human	IgG1
DMAb-1513-CQ	rOV-TL12/30	Mouse	Human	IgG1
DMAb-1514-CQ	RM284	Rabbit	Human	IgG	Human CK7 (Cytokeratin-7)
DMAb-0961-WJ	CK-7	Mouse	Human	IgG1	Cytoskeletal preparation of the RT4human bladder carcinoma cell line
DMAb-0964-WJ	KRT7/903	Mouse	Human	IgG1	Recombinant Full length human KRT7 protein
DMAb-1519-CQ	SPM270	Mouse	Human	IgG1
DMAb-0958-WJ	LP5K	Mouse	Human	IgG2b	Sonicated cytoskeleton fractions (insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes
DMAb-1521-CQ	CTKN7-1	Mouse	Human	IgG1	Recombinant Full length human KRT7 protein

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-KRT7 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0948-WJ)

Specifications

Target

Customer Reviews and Q&As

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