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anti-NY-ESO-1 (aa161-180) TCR, pCDTCR1 (TCR-L079Z)

The vector of anti-NY-ESO-1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human NY-ESO-1. The T cells are genetically modified through transduction with a retroviral vector expressing NY-ESO-1-specific T cell receptor. And the vector product was designed for the treatment of Melanoma .

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Details

  • Target
  • NY-ESO-1
  • Target Species
  • Human
  • Epitope
  • WITQCFLPVFLAQPPSGQRA
  • Format
  • Murinized and Cysteine-modified
  • HLA
  • HLA-A2
  • Targeting Diseases
  • Melanoma
  • Vector Name
  • pCDTCR1
  • Vector Length
  • 8kb
  • Vector Type
  • Lentiviral
  • Antibody Host
  • Murinized (from Human)

Target

  • Official Symbol
  • CTAG1A
  • Introduction
  • The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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