anti-pp50 (aa245-253) TCR, pCDTCR1(TCR-L095Z)

The vector of anti-pp50 T cell receptor (TCR) is constructed for the engineering of T cell to target CMV pp50. The T cells are genetically modified through transduction with a retroviral vector expressing pp50-specific T cell receptor.


Details


Target
pp50
Target Species
CMV
Epitope
VTEHDTLLY
Format
Codon optimized and cysteine modified TCR
HLA
HLA-A1
Targeting Diseases
CMV disease
Vector Name
pCDTCR1
Vector Length
8kb
Vector Type
Lentiviral
Antibody Host
Human

Target


Gene Name
CMV pp50 peptide
Official Symbol
pp50
Synonyms
65 kDa matrix phosphoprotein; 65 kDa phosphoprotein; Tegument protein pp65; Tegument protein UL83; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Cytomegalovirus infection
Introduction
CMV pp50 peptide VTEHDTLLY (HLA-A*0101) for stimulation of T-cells. Single peptide (VTEHDTLLY) for stimulation of human CMV pp50-specific CD8+ T-cells. The peptide is synthesised as it is presented by the MHC class I HLA-A*0101 allele. Lyophilized powder. Purity> 80 %, endotoxin free.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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