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Anti-PTPRC DNA-encoded mAb (DMAb), pVAX1 (DMAb-0158-YJ)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-PTPRC DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

  • Target
  • PTPRC
  • Vector Name
  • pVAX1
  • Vector Description
  • pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
  • Vector Promoter
  • CMV
  • Vector Tag or Fusion
  • Untagged
  • Delivery Method
  • Transfection
  • Cloning Method
  • Restriction Enzyme ⁄ MCS
  • Constitutive or Inducible System
  • Constitutive
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.
  • Background
  • DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

  • Entrez Gene ID
  • 5788
Sub CAT. DMAb Clone DMAb Host Target Species DMAb Isotype DMAb Immunogen  
DMAb-0158-YJ SPM496 Mouse Human IgG1, κ Stimulated human leukocytes were used as the immunogen for the LCA antibody.
DMAb-1879-WJ A20 Mouse Mouse IgG2a, κ SJL mouse thymocytes and splenocytes
DMAb-1880-WJ B-A11 Mouse Human IgG1 Thymus cells and Jurkat cell line
DMAb-1881-WJ B-C15 Mouse Human IgG1 Reh 6 cell line
DMAb-1882-WJ BHKG-2 Mouse Human IgG1
DMAb-1883-WJ BHPT-1 Mouse Human IgG1 Derived from the hybridization of mouse NS-1 myeloma cells with spleen cells of BALB/c mice immunized with peripheral blood monocytes from rheumatoid arthritis patient
DMAb-1884-WJ BRA-11 Mouse Human IgG1, κ Non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V)
DMAb-1885-WJ Bu78 Mouse Human IgG1
DMAb-0955-LY C11 Mouse Human IgG2a, κ
DMAb-1887-WJ C363.16A Rat IgG2a Murine CD45RB
DMAb-1888-WJ C455.1F Rat Mouse IgG2a
DMAb-1889-WJ CC1 Mouse IgG1
DMAb-1890-WJ CC76 Mouse Bovine IgG1
DMAb-1896-WJ EM-05 Rat Mouse IgG
DMAb-1897-WJ F10-89-4 Mouse Human IgG2a
DMAb-1898-WJ F8-11-13 Mouse Human IgG1
DMAb-1900-WJ GL24 Rat Mouse IgM Activated DBA/2 B cells
DMAb-1902-WJ HI100 Mouse Human IgG2b, κ
DMAb-1903-WJ HI30 Mouse Human IgG1
DMAb-1904-WJ HIS24 Mouse Rat IgG2b, κ
DMAb-1905-WJ HIS41 Mouse Rat IgG1
DMAb-1907-WJ I3/2.3 Rat IgG2b CD45 antibody (Azide free) was raised in Rat using CD45/LCA as the immunogen
DMAb-1908-WJ IBL-3/16 Rat Mouse IgG1 Purified B cells from mouse lymph nodes
DMAb-1909-WJ IBL-5/25 Rat Mouse IgG1, κ Mouse lymph node cells
DMAb-1910-WJ IBL-8 Rat Mouse IgG1, κ CD45RC (Mouse CD45RC)
DMAb-1911-WJ IH-1 Mouse Guinea Pig IgG1 Guinea pig leukemic B lymphocyte L2C cells
DMAb-1912-WJ IL-A116 Mouse Bovine IgG Bovine peripheral blood monouclear cells
DMAb-1913-WJ JS-83 Mouse Human IgG1, κ
DMAb-1914-WJ K252-1E4 Mouse Pig IgG1
DMAb-1916-WJ LT40 Mouse Chicken IgM
DMAb-1924-WJ ANK74 Mouse Rat IgG1 IL-2-activated cultured NK cells of Wag rats
DMAb-1931-WJ BRA-55 Mouse Human IgG1
DMAb-1933-WJ CA12.10C12 Mouse Dog IgG1
DMAb-1934-WJ CA4.1D3 Mouse Canine IgG1
DMAb-1936-WJ CDLA45RA-1 Mouse Human IgG2a, κ
DMAb-1937-WJ CDLA45RB-1 Mouse Human IgG1, κ
DMAb-1938-WJ CDLA45RO-1 Mouse Human IgG2a, κ
DMAb-1946-WJ UCH-L1 Mouse Human IgG2a IL-2-dependent T-cell line (CA1)
DMAb-1950-WJ DF-B1 Mouse Human IgG3, κ Extract from Alexanders hepatoma cell line L428 (Workshop V)
DMAb-1951-WJ E19-G Rabbit Human IgG Peptide derived from C-terminal sequence of human CD45
DMAb-1957-WJ HB220 Rat Mouse IgG2a
DMAb-1962-WJ IVA103 Mouse Bovine IgG1
DMAb-1963-WJ L12/201 Mouse Rabbit IgG1 Glycoproteins isolated from the T cell line, RL-5
DMAb-1965-WJ LT45 Mouse Human IgG2a
DMAb-1884-WJ BRA-11 Mouse Human IgG1, κ
DMAb-1897-WJ F10-89-4 Mouse IgG2a, κ Purified T cells from human lymph nodes
DMAb-1898-WJ F8-11-13 Mouse IgG1 Human T lymphocytes
DMAb-1902-WJ HI100 Mouse Human IgG2b, κ The immunogen was CD45RA
DMAb-1903-WJ HI30 Mouse IgG1 An amino acid sequence that is conserved among all CD45 isoforms
DMAb-1821-CQ HLe-1(2D1) Mouse Human IgG1 Human peripheral blood mononuclear cells
DMAb-1907-WJ I3/2.3 Rat IgG2b T1M1 (Thy-1--c) cells
DMAb-1823-CQ MEM-143 Mouse Human IgG1 Human peripheral blood lymphocytes
DMAb-1824-CQ MEM-28 Mouse IgG1 Human thymocytes and T lymphocytes
DMAb-1825-CQ MEM-56 Mouse Human IgG2b Human thymocytes and T lymphocytes
DMAb-1826-CQ PD7/26 Mouse Human IgG1, κ Human peripheral blood lymphocytes maintained in T cell growth factor
DMAb-1827-CQ PTPRC/1132 Mouse Human IgG1, κ Recombinant Full length human CD45RB protein
DMAb-1828-CQ PTPRC/1147 Mouse Human IgG1, κ Recombinant Full length human CD45RB protein
DMAb-1829-CQ SPM125 Mouse IgG2a, κ Cultured human T-cells from an IL-2-dependent T-cell line (CA1)
DMAb-0158-YJ SPM496 Mouse Human IgG1, κ Stimulated human leukocytes
DMAb-1831-CQ SPM568 Mouse Human IgG2a, κ Stimulated human leukocytes
DMAb-1832-CQ SPM569 Mouse Human IgG1, κ Human peripheral blood lymphocytes maintained in T cell growth factor
DMAb-1833-CQ SPM570 Mouse Human IgG1, κ Isolated neoplastic cells from T cell lymphoma
DMAb-1834-CQ T200/797 Mouse Human IgG2a, κ Recombinant human CD45RO protein
DMAb-1835-CQ UCHL1 Mouse IgG2a, κ Interleukin-2-dependent human T lymphocytes
DMAb-1836-CQ X148 Mouse Human IgG T cell lymphoma cells
DMAb-1837-CQ X16 Mouse Human IgG1 T cell Lymphoma cells
DMAb-1838-CQ YTH24.5 Rat Human IgG2b Human T lymphocytes
DMAb-1839-CQ T6D11 Mouse IgG2b
DMAb-1840-CQ MEM-55 Mouse Human IgG1
DMAb-1841-CQ Bra55 Mouse Human IgG1
DMAb-0955-LY C11 Mouse Human IgG2a, κ Human lymphocytes
DMAb-1950-WJ DF-B1 Mouse Human IgG3, κ Extract from Alexanders hepatoma cell line L428
DMAb-1844-CQ hCD45 Mouse Human IgG2a
DMAb-1845-CQ YAML 501.4 Rat Human IgG2a
DMAb-1849-CQ YW62.3 Rat Mouse IgG2b Mouse spleen cells
DMAb-1850-CQ C363-16A Rat Mouse IgG2a, κ Cloned mouse Th2 cell lines
DMAb-1851-CQ PAN-LCA Mouse Human IgG
DMAb-1852-CQ 135-4C5 Mouse Human IgG2b, κ Stimulated human leukocytes
DMAb-1853-CQ PTPRC/1460 Mouse Human IgG1, κ Human B lymphocytes for the CD45 antibody
DMAb-1885-WJ Bu78 Mouse Human IgG1
DMAb-1913-WJ JS-83 Mouse Human IgG1, κ The immunogen was CD45RA
DMAb-1856-CQ 111-1C5 Mouse Human IgG1, κ Stimulated human leukocytes
DMAb-1857-CQ YTH 80.103 Rat Human IgG2b
DMAb-M302-YC 5 Mouse Human IgG1 Recombinant Human CD45 protein
DMAb-M303-YC 104 Mouse Mouse IgG2a
DMAb-0180-CN OX-1 Mouse Rat IgG1 Rat thymocyte membrane glycoproteins.
DMAb-0181-CN OX-33 Mouse Rat IgG1 Purified Rat spleen CD45RA
DMAb-1850-CQ C363-16A Rat Mouse IgG2a Cloned mouse Th2 cell lines
DMAb-1823-CQ MEM-143 Mouse Human IgG1 Tissue/cell preparation (Human). Peripheral blood lymphocytes
DMAb-1840-CQ MEM-55 Mouse IgG1
DMAb-0185-CN OX-22 Mouse Rat IgG1 PHA stimulated rat lymphocytes
DMAb-1835-CQ UCHL1 Mouse Human IgG2a Human IL-2 dependent T cells

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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