Anti-TNFRSF18 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0641-YJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-TNFRSF18 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
TNFRSF18

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-011-YC	1A3	Mouse	Human	IgG1	Human recombinant protein fragment corresponding to amino acids 26-162 of human TNFRSF18(NP_004186) produced in E. coli
DMAb-672-YC	1C4	Mouse	Human	IgG2a	Human recombinant protein fragment corresponding to amino acids 26-162 of human TNFRSF18(NP_004186) produced in E. coli
DMAb-341-YC	3A7	Mouse	Human	IgG1	Human recombinant protein fragment corresponding to amino acids 26-162 of human TNFRSF18(NP_004186) produced in E. coli
DMAb-0644-YJ	5G4	Mouse	Human	IgG2a	Human recombinant protein fragment corresponding to amino acids 26-162 of human TNFRSF18(NP_004186) produced in E. coli
DMAb-0717-LY	9G8	Mouse	Human	IgG2b	Human recombinant protein fragment corresponding to amino acids 26-162 of human TNFRSF18(NP_004186) produced in E. coli
DMAb-0971-LY	2H4	Mouse		IgG2b, κ	Recombinant protein
DMAb-0761-LY	AP-MAB0860	Rat	Mouse	IgG2	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0762-LY	ELO1	Rat	Human	IgG2a	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0763-LY	MAB0860	Rat	Mouse	IgG2	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0764-LY	MGIT02	Rat	Mouse	IgG2a, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0765-LY	MGIT07	Rat	Mouse	IgG2a, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0750-LY	14L474	Rat	Mouse	IgG2	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0751-LY	14L475	Mouse	Human	IgG1	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0971-LY	2H4	Mouse		IgG2b, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0753-LY	6D39	Rat	Mouse	IgG2	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0754-LY	6D412	Rat	Human	IgG2a	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0755-LY	6D413	Rat	Mouse	IgG2a	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0756-LY	7C13	Rat	Mouse	IgG2	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0757-LY	7R12	Mouse	Human	IgG1	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0717-LY	9G8	Mouse	Human	IgG2b	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0759-LY	AIT158D	Rat	Human	IgG2a, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0739-LY	621	Mouse	Human	IgG1, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0740-LY	DT5D3	Mouse	Human	IgG1	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0741-LY	MM0313-7R12	Mouse	Human	IgG1	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0742-LY	RM0066-7C13	Rat	Mouse	IgG2	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0743-LY	T9P4G4/D7	Mouse	Human	IgG2b, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0744-LY	YGIR765.4.16	Rat	Mouse	IgG2b	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0745-LY	YGITR765	Rat	Mouse	IgG2b, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0746-LY	11K7	Mouse	Human	IgM	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0747-LY	11K8	Mouse	Human	IgG3, κ	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0748-LY	14L472	Rat	Mouse	IgG2	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0733-LY	108619	Rat	Mouse	IgG2a	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0734-LY	108626	Rat	Mouse	IgG1	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0735-LY	10C362	Rat	Mouse	IgG2b	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0736-LY	110416	Mouse	Human	IgG1	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18
DMAb-0737-LY	11E203	Rat	Mouse	IgG	TNFRSF18 Gene(Protein Coding) TNF Receptor Superfamily Member 18

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-TNFRSF18 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0641-YJ)

Specifications

Customer Reviews and Q&As

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